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omicron:’Study infrequent mutations to stay ahead of Covid’ | Mumbai News

omicron:’Study infrequent mutations to stay ahead of Covid’ | Mumbai News

 


Mumbai: As the Omicron-Covid wave continues to decline, experts said it is important to continue genomic surveillance of the SARS-CoV-2 virus that causes Covid.
Omicron Subspecies were detected in South Africa with continuous monitoring.Omicron may have existed for some time, but was hidden by the birth of the offensive. delta The variant that caused the megasecond wave in India. ” Shashan KujosiState members COVID Task force.
Scientists are now beginning to talk about the need to pay attention to “low frequency mutations” that are not found in most positive cases but can “escape” vaccine antibodies.
In a study published in the medical journal Frontiers in Microbiology, indexed a few days ago, the team at the CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB) in Delhi called for the need to track “low-frequency mutations.” I emphasized. He said it is important to match patient genomic sequencing with clinical data to understand mutations that can lead to “vaccine breakthrough” infections. Vaccine breakthrough is a term used to describe an infectious disease that occurs despite vaccination.
Main authors of the study Dr. Rajesh Panday He said that when the number of cases is decreasing, it is necessary to perform the sequence more vigorously. “It’s easy to find mutations that may later emerge as a problem due to’natural experiments’. If the tail of the wave is long, you need to identify the reason, such as some mutations, “he said. Breakthrough case viral genome sequencing helped scientists study how mutants reduced vaccine efficacy. For example, Delta has reduced the effectiveness of the vaccine due to mutations in the pesplomer.

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