For the first time, a British researcher Deafness When Epilepsy It is an early sign of Parkinson’s disease and is more likely to be diagnosed early in the future.
Their pioneering research was published in the journal JAMA Neurology Researchers at Queen Mary University of London investigated the early symptoms and risk factors of Parkinson’s disease among more than one million people living in East London between 1990 and 2018. Other ethnic groups make up about 45% of the inhabitants compared to 14% in the rest of the UK. It also has the highest level of deprivation in the UK. Eighty percent of the patients included in this study came from low-income households.
The lead author, Dr. Christina Simonet, a neurologist and PhD student at Queen Mary University of London, commented: “This is the first study focusing on the pre-diagnosis stage of Parkinson’s disease in such diverse populations with high socio-economic deprivation but universal access to health care.”
Two new early features of Parkinson’s disease
In their study, using electronic medical records, researchers said, “Known symptoms associated with Parkinson’s disease, such as tremor and memory problems, may appear 10 and 5 years before diagnosis, respectively. There is. “
In addition, they discovered two previously unknown early features of Parkinson’s disease, epilepsy and deafness. They were able to reproduce these findings using additional data from UK Biobank.
Dr. Alastair Neuss, a reader of neurology and neuroepidemiology at Queen Mary University of London, and one of the research authors said: PREDICT-PD researchWe want to identify people who are at high risk for Parkinson’s disease, even before they have obvious symptoms. “
Researchers pointed out that early signs of Parkinson’s disease had been previously explained, but “studies have focused primarily on the wealthy Caucasian population.”
“The new study uses data from such diverse and deprived urban populations for the first time to provide further evidence of risk factors and early signs of Parkinson’s disease,” they added.
Dr. Simonet said: ..
“Our results reveal new risk factors and early symptoms of epilepsy and deafness. Previous studies suggest a link, with epilepsy more common in Parkinson’s patients than in the general population. But more research is needed to fully understand it. Relationship. “
Raising awareness needed to avoid delays in diagnosis
Dr. Noyce said: In our study. “
Dr. Simonet added, “Primary care professionals can understand how quickly the symptoms of Parkinson’s disease appear, enable patients to be diagnosed in a timely manner, and enable doctors to act early and manage their condition. It’s important. “
In this East London population, the following conditions High blood pressure When Type 2 diabetes The researchers said it was associated with an increased probability of developing Parkinson’s disease, adding that a stronger association with memory impairment within this population was also observed than previously described.
Dr. Neuss emphasized: “If we can diagnose Parkinson’s disease early, we have a real opportunity to intervene early and provide treatments that have the potential to improve the quality of life of our patients.” We “in the future, delay or treat Parkinson’s disease.” You may be in a position to do it. “
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Sources
1/ https://Google.com/
2/ https://www.medscape.com/viewarticle/969762
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