Prenatal, intranatal, and postnatal mother-to-baby transmission of SARS-CoV-2 transmission is possible, but rare, and mothers need to be relieved, researchers say.
New research published in British Medical Journal (BMJ)Reported that less than 2% of all babies born to SARS-CoV-2 infected mothers were tested to be virus positive. Researchers also “see how maternal factors such as severe COVID-19, death, intensive care unit admission, and postnatal infection are associated with SARS-CoV-2 positivity in offspring. I also explained.
In this study, an international research team led by the WHO Global Women’s Health Cooperation Center at the University of Birmingham to assess the SARS-CoV-2 positive rate and timing of mothers born to SARS-CoV-2 infected mothers. I started. -Factors related to offspring infection and perinatal outcomes, and progeny SARS-CoV-2 status.
Severe mother’s risk of COVID-19 infection is a baby’s risk
To do this, they serve as the primary database, preprint server, and website for COVID-19 research (including Medline, Embase, Cochrane Database, and World Health Organization (WHO) COVID-19). Performed a live systematic review and meta-analysis of. Database-December 1, 2019-August 3, 2021. Two reviewers independently extracted data and evaluated the quality of the study – using the WHO classification to classify the timing of intrauterine, parturition, and early postnatal mother-to-child transmission, 472 studies. (206 cohort) study, 266 case series and case reports; 28 952 mothers, 18 237 babies) Included from 569232 identified articles.
Research leader Shakila Thangaratinum, a professor of maternal and perinatal health at the University of Birmingham, said: In utero, during and after childbirth. ”
Researchers have tested that 1.8% of 14,271 babies born to SARS-CoV-2 infected mothers are virus-positive. When limited to babies exposed to the virus before birth or during delivery, it decreases by a rate of 1%.
They also emphasized how babies are likely to be positive if “a woman is infected with severe COVID-19 or is diagnosed after childbirth”. Specifically, severely ill pregnant women COVID-19 (OR 2.4, 95% CI 1.3 to 4.4), maternal mortality (OR 14.1, CI 4.1 to 48.0), and maternal hospitalization in the intensive care unit (OR 3.5, CI 1.7 to 6.9). ). , And postnatal infections in pregnant women (OR 5.0, CI 1.2-20.1) were associated with SARS-CoV-2 positivity in offspring.
Vaginal delivery, skin-to-skin contact, breastfeeding are low risk
Professor Tanga Latinum said, “Parents and medical professionals can rest assured that only a small proportion of babies born to mothers who test positive for SARS-CoV-2. This is the risk of transmission to such babies. Means that is rare. “
The severity of maternal covid-19 infection appeared to be associated with SARS-CoV-2 positivity in offspring, but if the mother was infected with SARS-CoV-2, a trimester of maternal infection, at birth. Pregnancy, mode of delivery, breastfeeding, or mother-birth separation of babies was not associated with positive offspring, researchers said, Professor Tanga Latinam. Vaginal childbirth, Skin-to-skin contact and breastfeeding – all of this should be encouraged. “
Vaccination during pregnancy should be further encouraged
The research team recommends that babies born to mothers with severe SARS-CoV-2 are more likely to test positive and should be “tested and closely monitored after birth.”
“We should further encourage vaccination during pregnancy to prevent mothers’ infections and serious illness,” Tanga Latinam said. “Healthcare professionals and policy makers are SARS. -We need to be aware of the expected burden of being positive for CoV-2. ” In the case of babies, it can be transmitted at any time during pregnancy and childbirth, “and this” emphasizes the need for appropriate measures to reduce the risk of postnatal viral infection. “
Researchers said they would analyze new studies as more evidence became available to investigate the effects of the SARS-CoV-2 variant and vaccination of concern on newborns.
