Health
Ivermectin not useful for the treatment of COVID-19, large study found
March 31, 2022- IvermectinPopular antiparasitic drugs as an alternative treatment to COVID-19 showed no signs of quelling the disease or reducing the risk of hospitalization for patients. Large clinical trial Was announced in New England Journal of Medicine..
The findings largely exclude drugs as a treatment for COVID-19, the study authors write.
“There is really no benefit,” said David Boulware, MD, a co-author of the University of Minnesota and one of the infectious disease specialists. Said New York Times..
Researchers shared a summary of the results during August 2021 Online presentation Sponsored by the National Institute of Health. The complete data has never been published.
“Now people can dive into details and data. Hopefully it will lead the majority of doctors from ivermectin to other treatments,” Boulware said.
In the trial, the research team compared more than 1,350 infected people. coronavirus Ivermectin or placebo As a treatment.
Between March and August 2021, 679 patients received a daily dose of ivermectin over a three-day period. Researchers found that ivermectin did not reduce the risk that people with COVID-19 were hospitalized or went to the emergency room within 28 days of treatment.
In addition, the researchers examined a specific group to understand whether some patients benefited for some reason, such as taking ivermectin immediately after a COVID-19-positive test. However, those who took the drug during the first three days after a positive coronavirus test performed worse than those in the placebo group. The drug also did not help the patient recover faster.
Researchers have found that treatment with ivermectin “has no significant effect” on the number of days people spend in the hospital, the number of days hospitalized people need a ventilator, or the risk of death. wrote.
Ivermectin Pandemic..
For decades, the drug has been widely used in the treatment of parasitic infections. At the beginning of the pandemic, researchers checked thousands of existing medicines for the coronavirus to determine if potential treatments already existed. Laboratory experiments on cells have suggested that ivermectin may work, Times report.
However, some researchers pointed out that the experiment worked because of the high concentration of ivermectin used. This is a much higher dose than it is safe for people. Despite concerns, some doctors have begun prescribing ivermectin to their patients.After receiving reports from people who need medical attention, especially after using livestock formulations, the FDA Issued a warning The drug was not approved for use with COVID-19.
Researchers around the world have done small things Clinical trials The newspaper reported to understand whether ivermectin treats COVID-19. At the end of 2020, Andrew Hill, MD, a virologist at the University of Liverpool in the United Kingdom, reviewed the results of 23 trials and concluded that the drug could reduce the risk of death from COVID-19. rice field.he Publish the results July 2021, but Later report Many of the studies were flawed and at least one was found to be fraudulent.
Hill withdrew the original study, Started another analysis, Published in January 2022. In this review, he and his colleagues focused on the studies that were least likely to be biased. They found that ivermectin was useless.
Recently, Hill and his colleagues performed another analysis using new data from a Brazilian trial, but again they did not see any benefit.
Some clinical trials are still testing ivermectin as a treatment, Times It has been reported and results are expected in the coming months. After reviewing data from a Brazilian trial of ivermectin and various other drugs tested against COVID-19, some infectious disease experts said that ivermectin does not help people with COVID-19. Some say it’s more likely to see. ..
“We welcome the results of other clinical trials and open our hearts to see them,” said Paul Sachs Medicine, an infectious disease expert at Brigham and Women’s Hospital, who monitors drug data throughout the pandemic. The doctor told the newspaper. ..
“But at some point, continuing to study the unlikely approach would be a waste of resources,” he said.
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