Health
Magic Mushroom Improves Brain Connections to Relieve Depression
(Bloomberg)-Magic Mushrooms connect more isolated areas of the brain in people with depression, paving the way for treating conditions differently than traditional medicines.
Researchers at Imperial College London have found that the fungal hallucinogen psilocibin has helped “open” and improve communication in the brain for up to three weeks. According to a study published in the journal Nature Medicine, the result was a liberation effect not seen with the traditional antidepressant Lexapro.
A new therapeutic approach is needed because one in three patients cannot achieve complete recovery with existing first-line treatments. The World Health Organization estimates that up to 5% of adults worldwide suffer from depression, making it difficult to engage in daily activities.
“These discoveries are important because for the first time we found that psychedelics work differently than traditional antidepressants. The brain becomes more flexible and fluid, and negative thoughts associated with depression. It’s harder to settle in the pattern, “said David Nutt, head of the empire. Senior author of the Psychedelic Research Center and thesis.
The team examined the patient’s brain scans before and after the patient was given psilocybin-assisted therapy or a traditional antidepressant, a drug chemically known as escitalopram. They found that antidepressants have a milder and slower effect than the ingredients in magic mushrooms.
Doctors may need to determine which approach is suitable for different patients, Nat said. Within a few years, he said, people may have the option of taking daily pills or having a psychedelic experience.
The brains of people with depression usually have circuits that are more isolated from each other. This is a condition associated with negative cognitive bias, strict thinking patterns, and fixation regarding oneself and the future. Studies have found that psilocybin helps areas of the brain communicate better with each other, allowing patients to experience “emotional liberation,” optimism, and more psychological flexibility.
The findings are a precursor to research into other mental illnesses. Nutt’s team is currently studying the use of psychedelics for loss of appetite and hopes to secure funding to test psychedelics as a treatment for addiction.
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