Health
COVID vaccine protects people with IBD
Studies have found that the COVID-19 vaccine can safely and effectively protect people with inflammatory bowel disease from the SARS-Cov-2 virus.
In this study, researchers focused on all studies that accounted for the response of patients with inflammatory bowel disease (IBD) who received the COVID-19 vaccine.
Sick people are generally treated with suppressive medications Immune system He reported concerns about whether such treatment might diminish their response to the vaccine.
“We wanted to systematically demonstrate that the vaccine safely protects IBD patients from COVID-19,” said a study, Senior IBD Fellow of Gastroenterology and Hepatology, Rutgers University Robert Wood Johnson Medical College. Author Abhishek Bhurwal states. .. “Our systematic reviews and meta-analyses have confirmed that the vaccine is safe and works well for our patients.”
An estimated 3.1 million adults in the United States Diagnosed with IBDAccording to the Centers for Disease Control and Prevention. This disease, including Crohn’s disease and ulcerative colitis, causes chronic inflammation of the gastrointestinal tract. The number of such patients is increasing, says Bhurwal.
Research published in Gastroenterological pharmacology and therapeuticsFocuses on four important aspects of COVID-19 vaccination in IBD patients. The strength of the immune response to the vaccine. Occurrence of breakthrough infections after vaccination; Occurrence of adverse events to the vaccine; Whether different IBD treatments affected vaccine efficacy.
As a result of the analysis, we found the following.
- Vaccinated IBD patients showed high levels of antibody response known as seroconversion two weeks after the first vaccination. This shows a strong positive reaction to the vaccine. The response was even higher after two doses compared to one dose.
- Vaccinated IBD patients did not experience higher or lower breakthrough infection rates than controls in the study. However, the studies analyzed may not have been designed to allow for more subtle distinctions. In addition, further studies on the efficacy of mutants and booster immunization are needed.
- Vaccinated IBD patients had a lower incidence of adverse events, with the most common events also seen in the general population. Reaction at the injection site. Headache; low back pain; and joint pain.
- Vaccinated IBD patients who received different immunosuppressive treatments responded similarly to the vaccine. Further research is needed to evaluate patients taking IBD corticosteroids.
Due to treatment with immunosuppressive drugs, IBD patients are more susceptible to infections than the general population. As a result, they are encouraged to receive the COVID-19 vaccine.
“Members of the IBD population ImmunodeficiencyIt was important to document that the SARS-CoV-2 vaccine works for them, “says Bhurwal. “This analysis suggests that a double dose of the SARS-CoV-2 vaccine is safe and effective in the IBD population, but further studies on booster effects and COVID variants are needed.”
Source: Rutgers University
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