Health
Magic mushrooms can help “open” the brains of people with depression: research
The psychedelic compounds contained in psychedelics, commonly known as magic mushrooms, help “open” the brain of a depressed person and allow areas of the brain to speak more freely to each other. Potential Treatments for Mental Illness Several studies have tried synthetic forms of medicine to treat patients with depression and anxiety with promising results. The team at the Psychedelic Research Center at Imperial College London believes they have elucidated how psychedelics can be therapeutic.
New results from two combined studies, including about 60 adults, showed that people who responded to psilocybin supportive care showed increased brain connectivity not only during treatment, but up to the next three weeks. It is clear.
This “opening” effect was associated with self-reported improvement in depression.
However, similar changes in brain connectivity have not been seen with those treated with conventional antidepressants (called escitalopram), suggesting that psychedelics work differently in the treatment of depression.
According to the team, the findings published in the journal Nature Medicine are promising advances in psilocybin therapy, the effects of which have been replicated in two studies.
They say that patterns of brain activity in depression can be rigid and restricted, and psilocybin can help the brain get out of this rut in ways that conventional treatments cannot. Explaining.
“The effects seen with psilocybin are consistent in two studies related to improving people and not with traditional antidepressants,” said Robin Carhartt Harris of the University of California, San Francisco. The professor says.
“Previous studies showed similar effects on the brain when scanned with psychedelics, but here they are seen weeks after treatment for depression, suggesting a carry-over of acute drug effects. “I’m doing it,” said Harris, a former director of the Imperial Center for Psychedelic Research.
The researchers added that the first changes in brain activity one day after treatment were a good predictor of whether a person would still show improvement at 6 months, while follow-up data were still being analyzed for participants. I did.
However, they warn that depressed patients should not attempt self-treatment with psilocybin, as taking magic mushrooms or psilocybin without safeguards may not give good results. bottom.
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