Health
New study: common medications found to be effective against mild and moderate Covid
Common anti-inflammatory drugs have been found to be effective antiviral agents for mild and moderate treatment. COVID-19 Patience. The drug indomethacin is widely used to treat various types of inflammation-related symptoms. A study of Covid patients by IIT Madras Nature Scientific Reports..
medicine: Indomethacin is a non-steroidal anti-inflammatory drug that can be taken orally as capsules and liquid suspensions. According to the National Library of Medicine, indomethacin works by stopping the body’s production of substances that cause pain, fever, and inflammation. It is used to relieve moderate to severe pain, tenderness, swelling, stiffness and inflammation of the shoulders caused by various arthritis.
Investigation result: The randomized clinical trial was conducted by IIT Madras researchers at the Panimalar Medical College and Research Institute in Chennai. Of the 210 hospitalized patients, 107 were randomly assigned to the control group and treated with paracetamol and standard of care, and 103 patients received indomethacin with standard of care, media from IIT Madras. The release said.
None of the 103 patients who received indomethacin developed decreased oxygen saturation, but 20 patients in the control group were unsaturated (saturation levels <93%). Patients in the indomethacin group recovered from all symptoms in 3-4 days, but the control group took twice as long.
Liver and kidney function tests showed no side effects. In a 14-day follow-up, it was announced that nearly half of the patients in the control group showed some discomfort and some of the patients with indomethacin complained only of fatigue.
Previous findings: In a previous study by the same team Indian Medical Association Journal, 72 patients received indomethacin and 72 other patients received paracetamol. Only one patient receiving indomethacin treatment developed hypoxia compared to 28 patients in the paracetamol group. Administration of indomethacin to patients with Covid symptoms prevented the need for ventilation, Release said.
“Indomethacin works in all mutants. We made two trials, one in the first wave and the other in the second wave. The results were the same,” the researchers said. Professor Rajan Ravichandran was reported to have said.
study: “Open-label, randomized clinical trial of indomethacin in mild and moderately hospitalized Covid-19 patients”, Rajan Ravichandran et al, Nature Scientific Reports..
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