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UK authorities are focusing on the possible association of adenovirus with cases of hepatitis in children


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UK health officials have released new details in an ongoing investigation of an abnormal series of hepatitis cases in children. The new report will help explain why they focused on the possibility of linking to the adenovirus family, the UK Health and Security Agency released on Monday.

Since the beginning of this year, at least 111 children in the UK have been confirmed to have acute liver inflammation, but this does not appear to be due to a group of hepatitis viruses that are likely to be the cause. More cases have been published in the United States and other countries around the world.

About three-quarters of 53 children tested for adenovirus in the UK I’m back positive. On the other hand, the virus that causes Covid-19 was found in only one-sixth of the children tested. This is consistent with the level of community infection in the United Kingdom.

Adenoviruses make up a large family of viruses that can spread from person to person, causing a variety of illnesses such as the common cold, conjunctivitis, and gastroenteritis. It is rarely reported as the cause of severe hepatitis in healthy people.

However, these hepatitis cases occur with other common viruses whose adenovirus epidemic has spread in recent months and has surged at the end of Covid-19 precautions and behavior that repels most bacteria. ..

After a dramatic decline during the pandemic, documented cases of adenovirus surged and are now at higher levels than the UK saw before Covid-19.

Studies have circulated around adenovirus, but it is still unclear how it causes liver inflammation. According to experts, the virus may be just one of the factors that leads to these cases when it occurs with something else.

“There may be cofactors that cause normal adenovirus to cause more serious clinical symptoms in young children,” the UK Health Agency said. Technical briefing Monday, “Reduced exposure during a pandemic, increased susceptibility to previous SARS-CoV-2 or other infections, or undiscovered coinfections or toxins, or the emergence of new strains of adenovirus with altered properties. You may have done it. ”

Experts say another possibility may be timing. As babies grow older, they may be children who would normally have been infected with minimal symptoms, as they are reacting more seriously to the virus.

British scientists are looking at certain types of adenovirus for blood sample data, but their genetic makeup needs to be examined as confirmation.

According to the UK Health Security Agency, cases are primarily children under the age of 5, with a median age of 3 and “only a few children over the age of 10 are being investigated.” Dozens of people have recovered and no deaths have been reported in the UK, but 10 children need liver transplants.

Saturday, World Health Organization said At least 169 cases of acute childhood hepatitis have been identified in 11 countries, of which at least 17 have died from liver transplants.




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