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Researchers studying COVID-19 recurrence after using Paxrovid

Researchers studying COVID-19 recurrence after using Paxrovid

 


April 29, 2022-US researchers plan to investigate the frequency and reasons for recurrence of coronavirus levels in some COVID-19 patients taking Pfizer’s Paxrovid drug. To Bloomberg News..

The CDC and the National Institute of Infectious Diseases are reviewing various epidemiological and clinical studies to determine the likelihood of recurrence after 5 days of antiviral treatment. ..

“That’s a priority,” Dr. Clifford Lane, MD, Deputy Director of Clinical Research at the Institute, told Bloomberg News that the question is “very urgent for us to deal with.” I added.

Paxrovid treatment is becoming an increasingly more part of the Biden administration Pandemic The approach, the press reports, is more widely available in pharmacies nationwide.

So far, researchers know little about rebound cases. The media reported on how often they occur, whether the Omicron variant may play a role, and whether the drug is associated with recurrence in the first place. Scientists want to learn more so that doctors can find out how to help patients who experience a recurrence of the infection after receiving Paxrovid treatment.

Earlier this week, researchers at VA Boston Healthcare Systems Preprint released In a case study marking the first rebound case described in the medical literature. A 71-year-old man who was vaccinated and boosted recovered from COVID-19 shortly after taking Paxrovid, but symptoms relapsed and virus levels soared about 9 days after the first positive test. .. After that, the symptoms and virus levels resolved after a few days.

Similar cases have appeared on social media and medical blogs, and doctors have been seeing patients with this type of rebound in recent weeks.

“Health providers trying to prescribe this should be aware that this phenomenon will occur. Even if symptoms worsen after Paxrovid, it is probably COVID,” said the Infectious Diseases Department at Brigham and Women’s Hospital. The clinical director, Dr. Paul Sachs, said. He told Bloomberg News.

Saxophone Wrote about Rebound after Pax Rovid I saw alone a few weeks ago HIV Patience.

Pfizer’s final trials showed that a small number of patients experienced rebound after treatment. The FDA previously stated that it “evaluates viral load rebound reports after completion of Paxlovid treatment and shares recommendations as needed.”

“The big problem was that this information wasn’t on the label when the drug was released,” Sax said.

Future CDC and National Institutes of Health research will seek to understand how and why rebounds occur. Some people may need longer than standard 5-day treatment if they appear to be associated with new mutations such as Omicron or risk factors for certain patients.

“There are two things that suppress the virus: the drug and the host’s immune response,” Lane said. “If you stop the drug before the host’s immune response begins, you may see the virus come back.”

Sources

1/ https://Google.com/

2/ https://www.webmd.com/lung/news/20220429/researchers-to-study-covid-19-relapses-after-paxlovid-use

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