Health
The cause of melanoma beyond UV rays is why a skin examination is needed
Melanoma is the most deadly type of skin cancer. Melanoma occurs when melanocytes, the cells that produce pigment in the skin, are damaged, mutated, and begin to grow unsuppressed.
Sunlight or ultraviolet (UV) exposure is usually considered a risk factor for the development of melanoma, but the fact that melanoma can occur anywhere in the body is a patch of skin that never sees the light of day. Even so, UV radiation exposure is the only reason for melanoma.
According to the American Cancer Society, genetic changes associated with melanoma are usually acquired during a person’s life and, in some cases, appear to occur randomly within the cell. Melanoma not caused by UV exposure indicates changes in the C-KIT gene. People who develop melanoma may also inherit the gene from their parents. These melanomas are often caused by changes in tumor suppressor genes, rather than the genes that help cells grow, divide, and survive, known as oncogenes. Tumor suppressor genes are thought to regulate cell proliferation. If cells do not function properly due to inherited changes or other damage, they can grow out of control and lead to melanoma.
The Mayo Clinic says there may be additional environmental factors that damage the DNA of skin cells and cause melanoma, but the cause of cell damage is not always clear. However, the following risk factors should be in the minds of all and should serve as a motivation behind regular skin tests and healthcare visits.
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Has a history of beautiful skin and sunburn
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Excessive UV exposure
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Live near the equator or at high altitude
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Have more than 50 normal moles on your body
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Family history of melanoma
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Existence of weakened immunity due to illness or medicine
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People who are worried about melanoma can get to know their skin and learn about their family history, so they can better know about abnormalities and risk factors.
Mucosal melanoma is a rare form of melanoma that accounts for about 1 percent of all cases. According to Everyday Health, mucosal melanoma can occur in the sinuses, nasal passages, vagina, anus, oral cavity, and other internal areas that are unlikely to be exposed to the sun or other UV rays. Researchers were unable to identify risk factors for mucosal melanoma because neither UV exposure nor family history appeared to be involved in its development.
-Metro Creative Connection
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