Health
CDC: COVID booster blunts Omicron’s impact on nursing homes
Researchers have found that the additional booster immunization of the COVID vaccine helped significantly reduce the infection rate of nursing home residents during the Omicron wave compared to the primary series alone.
After adjustment, the relative vaccine efficacy (VE) of the additional dose of COVID vaccine was 46.9% (95% CI 44.8-48.9) in preventing cases in this population, said Namrata Prasad, PhD, and colleagues at the CDC. Writes as follows. Weekly morbidity and mortality reports..
“The relative VE estimates in this study are slightly lower and may reflect the reduction in VE due to potential antigenic escape of the Omicron mutant. This is Omicron compared to adult delta mutant infections. Consistent with the results of other studies showing low VE for mutant infections. “
They examined data from the CDC’s National Healthcare Safety Network from February 14th to March 27th, 2022, during Omicron’s surge. Approximately 15,000 skilled nursing facilities provided both case count reports and resident count reports, along with vaccination status based on reports two weeks ago.
The weekly report included approximately 1 million nursing home residents, two-thirds of whom received additional or additional doses. Only 22% received only the primary series. Almost all (more than 90%) were vaccinated with the mRNA vaccine.
Infection rates declined throughout the study period, but infection rates were “consistently lower” among additional or additional-dose residents compared to those in the primary series alone. The authors stated that there were 7,510 cases during the 1,509,674 residence week of the primary series alone, and 11,334 cases during the additional or additional dose of 4,416,401 residence week. This corresponds to a crude infection rate of 5.0 vs. 2.6 per 1,000 resident weeks, respectively.
However, Prasad’s group added that time because the vaccination could not be evaluated. National vaccination rate data show that by early December 2021, more than half of nursing home residents had been boosted or boosted.
Another limitation was the lack of control over unmeasured confounding factors such as age, comorbidity, previous COVID infection, or behavior associated with the risk of COVID infection.
Prasad et al. Emphasized the importance of additional primary and additional doses for residents with weakened immunity, as well as booster doses for residents of nursing homes.
“Efforts to keep vaccinations up-to-date for Nursing Home residents should be carried out in conjunction with other COVID-19 prevention strategies, including testing and vaccination of Nursing Home staff and visitors,” they said. Wrote.
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The authors do not disclose conflicts of interest.
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