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The use of anti-inflammatory drugs can prolong back pain




New studies question the traditional wisdom of treating back pain with anti-inflammatory drugs such as steroids and ibuprofen when exercise and other non-drug therapies do not work immediately.

Although these medicines relieve acute pain, they may actually increase the chances of developing chronic pain. Scientific translation medicine.. This study shows that inflammation is a normal part of recovery from painful injuries, and suppressing inflammation can make chronic pain more difficult to treat.

“For decades, treating pain with anti-inflammatory drugs has been the standard medical practice,” said Jeffrey Mogil, a professor of psychology. McGill University said In the school news release. “But it turns out that this short-term fix can lead to long-term problems.”

Researchers have investigated because back pain is so common. Twenty-five percent of adults in the United States say they have had back pain in the last three months. According to the CDC.. Acute low back pain is defined as lasting less than 4 weeks, and chronic low back pain is defined as lasting 12 weeks or longer.

By examining blood samples, researchers found that people with low back pain had high inflammation caused by neutrophils, a type of white blood cell that helps the body fight the infection.

“Neutrophils dominate the early stages of inflammation and set the stage for repairing tissue damage. Inflammation occurs for some reason, and it seems dangerous to interfere with it,” Mogil said in a news release. I said in.

The researchers found that blocking neutrophils in mice increased pain in animals by up to 10 times. According to a news release, administration of anti-inflammatory drugs and steroids to mice also prolonged the pain.

McGill University said other studies would support the findings. The school quoted an analysis of 500,000 people in the United Kingdom. Analysis showed that people taking anti-inflammatory drugs for pain were more likely to feel pain after 2 to 10 years.

Researchers sought not only observations of people with back pain, but also human clinical trials, saying the study suggests it’s time to rethink how pain is treated. ..

Experts warned about accepting the results without further investigation.

“It’s interesting, but more research is needed,” said Stephen J. Atlas, director of primary care research and quality improvement networks at Massachusetts General Hospital. New York Times..




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