Breakthrough Covid infection more likely in patients with cancer, Alzheimer’s disease

Breakthrough cases of Covid-19 leading to infection, hospitalization and death cancer Patients with Alzheimer’s disease, according to two new studies.

A “breakthrough infection” is when a fully vaccinated person becomes infected with Covid. Researchers at Case Western Reserve University School of Medicine cancer Alzheimer’s disease is also generally susceptible to infections and is the most vulnerable to the serious health consequences of Covid infections in the population.

The first study, recently published in the Journal of the American Medical Association (JAMA) Oncology, analyzed electronic health records of more than 636,000 vaccinated patients, including more than 45,000 vaccinated patients. .. cancer..

The team found that the overall risk of a breakthrough Covid infection in people vaccinated with cancer was 13.6% compared to 4.9% in people vaccinated without cancer. Did.

Pancreatic cancer had the highest risk of breakthrough infection in 24.7%, followed by liver cancer (22.8%), lung cancer (20.4%), and colorectal cancer (17.5%). ..

Cancers with a low risk of breakthrough infections include the thyroid gland (10.3%), endometrium (11.9%), and breast (11.9%).

The overall risk of hospitalization after a breakthrough infection in cancer participants was 31.6%, while the risk of death after a breakthrough infection was 6.7%.

“This study significantly increases the risk of breakthrough infections of Covid-19 in patients vaccinated against cancer, especially those receiving aggressive cancer treatment, and varies significantly depending on the type of cancer. “, Said Rong Xu, a professor of biomedical informatics at the School of Varsity Medicine.

In a second study published in the journal Alzheimer’s & Dementia, the team examined anonymous electronic health data from more than 262,847 adults aged 65 and over who were vaccinated between December 2020 and August 2021. I did.

Patients vaccinated against dementia show an overall risk of breakthrough infections ranging from 10.3% of Alzheimer’s disease to 14.3% of Lewy body dementias and are vaccinated without dementia. It was significantly higher than 5.6% of the elderly who received it.

“To protect this vulnerable population, continued vigilance is needed after vaccination. Caregivers consider continuous masking and social distance, and additional vaccines to protect these individuals. We need to, “said Pamela Davis, a professor of medicine.

–IANS

rvt / svn /

(Only the headings and images in this report may have been recreated by Business Standard staff. The rest of the content is automatically generated from the syndicated feed.)

Dear reader,

Business Standards has always worked hard to provide you with the latest information and commentary on developments that are of interest to you and have a wide range of political and economic impacts on the country and the world. Your encouragement and constant feedback on how to improve our offerings only strengthened our determination and commitment to these ideals. Even during these difficult times resulting from Covid-19, we keep you up-to-date with credible news, authoritative views, and sharp commentary on issues of relevant topics. I will continue to promise to keep it.
However, there is a request.

We need more help to continue to provide higher quality content to combat the economic impact of the pandemic. Our subscription model has seen encouraging reactions from many who subscribe to our online content. Increasing your subscription to online content only helps you reach your goal of delivering better, more relevant content. We believe in free, fair and reliable journalism. Your support through more subscriptions will help us practice the journalism we are committed to.

Supporting high quality journalism, Subscribe to business standards..

Digital editor