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Studies have found that brain fog and other long Covid symptoms can last for more than a year.

Studies have found that brain fog and other long Covid symptoms can last for more than a year.

 


A study published on Tuesday found that long Covid’s catastrophic neurological effects could last for more than a year, even if other symptoms were alleviated.

Studies published in the journal Annual clinical and translational neurology reportIs the longest follow-up of neurological symptoms in long Covid patients who have never been hospitalized in Covid.

Neurological symptoms such as brain fog, numbness, tingling, headache, dizziness, blurred vision, tinnitus, and malaise are most often reported.

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A new study by researchers at Northwestern University Short-term research Focused on 100 long Covid patients, published last spring. According to the study, 85% of patients reported at least 4 persistent neurological problems at least 6 weeks after acute infection.

For follow-up, the team continued to investigate 52 former participants who were patients at the University Neuro COVID-19 Clinic — Long Covid Clinic — Up to 18 months. The cohort was three-quarters of women, with an average age of 43 years. Almost 80% were vaccinated and all showed mild Covid symptoms that did not require hospitalization.

Studies have shown that most neurological symptoms persisted after an average of 15 months.Although most patients reported their improvement Cognitive function Fatigue, symptoms did not disappear completely and still affected their quality of life.

“Many of these patients have cognitive deficits that prevent them from working as before,” said Igor Coralnick, co-leader of the study and head of neuroinfection and global neurology in northwestern medicine. The doctor says. He oversees the Neuro COVID-19 Clinic.

The study also found that while some symptoms, such as heart rate and blood pressure fluctuations, and gastrointestinal problems, increased over time, taste and smell loss tended to improve. Covid vaccination did not relieve symptoms, but it did not exacerbate long Covid.

Studies in the northwest do not investigate why some of the symptoms persist and others disappear, or why they occur in the first place.

“The next step in this is to find out what caused the long Covid in the first place and why some people get it and some don’t,” says Koralnik.

Dr. Avindra Nath, director of the National Institute of Public Health’s National Institute for Neurological Disorders and Stroke, who was not involved in the new study, said one hypothesis is that the symptoms of long Covid patients are the Inflammatory reaction of the body To coronavirus. Viral infections activate inflammatory cells throughout the body, including the brain. Inflammation aims to attack invading viruses, but in the process it also damages brain cells and neurons. SARS-CoV-2, the virus that causes Covid, causes a particularly strong inflammatory response, he said.

“Covid is probably the most serious respiratory illness we’ve ever experienced, so it’s not surprising that Covid has long-term effects,” says Nath.

Dr. Panagis Galliazzatos, MD Assistant Professor of Johns Hopkins Medicine in Baltimore and Physician of Pulmonary and Critical Care, was not involved in the study, but experts have long a natural healing process for Covid symptoms.He said it would inform further research exploring treatment and hopefully ways to provide early diagnosis.

According to Galiatsatos, fighting the virus is a burden to the body, so it is normal for patients to experience fatigue and other symptoms during the normal recovery process after infection. “But healing shouldn’t last more than six months,” he said.

“Now we need time to distinguish between the two groups,” he said. “Patients just have to wait, which is really frustrating. But with biomarkers to test, long Covids can be identified and intervened early.”

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However, biomarker searches have so far not yielded results.

In another study, on Monday Annual report of internal medicineResearchers at the National Institute of Infectious Diseases, another branch of NIH, conducted a comprehensive medical test on 189 long Covid patients.

The trial included more than 130 cognitive, blood, and imaging diagnostic tests. They also looked for biomarkers that signal heart and brain damage, as well as kidney and liver damage.

Results were compared to the same trial conducted in 120 people without the use of long Covid. No difference was confirmed.

“Despite a thorough investigation, Dr. Michael Sneller, NIH’s infectious disease specialist and lead research author,” could not show evidence of organ damage, “or stated other physical differences. ..

This should not be interpreted to mean that Covid’s long-term patients have not experienced a real illness, Sneller said. Something is happening. Modern medicine has never been able to understand what is happening.

“No doubt, these people are really suffering,” he said. “We haven’t given up.”

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