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Your daily vitamin D from tomatoes?Gene tweaks could make that happen-consumer health news

Your daily vitamin D from tomatoes?Gene tweaks could make that happen-consumer health news

 


Tuesday, May 24, 2022 (HealthDay News)-Genetically engineered tomatoes could one day be comparable to salmon as a dietary source of vitamin D if early research is successful.

British scientists used the gene “editing” to make tomatoes. Tomatoes are packed with provitamin D3, a precursor that the body can convert. Vitamin D..

Gene tweaks usually targeted tomato enzymes that convert provitamin D3 to cholesterol. Gene editing interrupted the process and yielded precursor-rich tomato fruits.

Researchers said tomatoes could provide the same amount of vitamin D as 28 grams of tuna or two eggs.

“We have produced a source of plant-based vitamin D3. Vegan When vegetarian“. Principal Researcher Cathie Martin is a professor at the John Innes Center, a plant science research center in Norwich, England.

She said it was important. This is because few foods naturally contain vitamin D, all of which are animal foods, including fatty fish (such as tuna and salmon) and egg yolks.

In the United States, Vitamin D is also added to certain foods such as milk and many non-dairy milk and breakfast cereals.

As such, vitamin D deficiencies, and overt deficiencies, are less common in the United States than in many other places. This includes Europe, which “dislikes” adding vitamin D to foods, Martin said.

In fact, according to researchers, an estimated 1 billion people worldwide have inadequate vitamin D levels.

And, despite fortification, about a quarter of Americans still have inadequate vitamin D levels, the study authors pointed out. The risk is higher in certain groups, such as the elderly and those with dark skin. When the skin is exposed to sunlight, the body naturally synthesizes vitamin D, which is less efficient in the elderly and those with darker skin.

Vitamin D deficiency is considered a major public health problem because nutrients play an important role in the body. It keeps bones strong, contributes to normal nerve and muscle function, and supports immune defense.

In short, Martin said he has more Foods full of vitamin D That would be good.

The new work will be explained online on May 23rd. Natural plants, Martin’s team turned to CRISPR technology. With this tool, researchers can accurately “cut” a bit of DNA in a gene to change its function.

Here, the researchers made a small edit to the tomato gene, which regulates the enzyme that converts provitamin D3 to cholesterol (7-dehydrocholesterol reductase).

For those skeptical of “Frankenfood,” Martin emphasized that gene editing does not introduce foreign DNA into plants. And the researchers did not discover the unintended effects of editing on other tomato genes.

Why not take a vitamin D supplement or eat fortified cereals?

“I have no problem taking the pill,” Martin said. “But it’s much better to eat plant-based foods.”

She said tomatoes provide additional nutrients such as fiber, vitamin C and lycopene.

Amanda Palmer, an associate professor of international health at the Johns Hopkins School of Public Health in Baltimore, said:

Palmer, who was not involved in the study, is studying “bio-enhancement.” This includes using genetically modified rice to provide vitamin A and addressing the problem of vitamin A deficiency in low-income countries.

She called the new study “exciting,” but it was also an early proof of concept. Many questions remain, Palmer said: How stable is Provitamin D3 between storage and processing? How well is it absorbed by the body? And does it really change the state of vitamin D in consumers?

Palmer said biofortification is usually done using staple food crops that are part of the culture’s daily diet, such as rice and corn.

It’s unclear if tomatoes can be consumed to the extent that they “affect public health,” Palmer said.

Researchers believe that genetically modified tomatoes offer another potential benefit. Provitamin D3 levels are especially high in the leaves of tomato plants and are usually discarded. Instead, Martin said growers can extract vitamins from greens for use in supplements.

She said it could provide producers with an economic incentive to produce tomatoes, as well as providing a source of vegan-friendly supplement vitamin D.

“They were able to make money from waste,” Martin said. Theoretically, this means that the tomatoes themselves can be priced in the same way as traditional ones.

Researchers already have answers to another important question about genetically edited tomatoes. “Yes,” Martin said. “They taste like tomatoes.”

For more information

National Institutes of Health Vitamin D.

Source: Cathie Martin, PhD, Professor, John Innes Center, Norwich, UK; Dr. Amanda Palmer, Associate Professor of International Health, Human Nutrition Center, Johns Hopkins Bloomberg School of Public Health, Baltimore. Natural plantsMay 23, 2022, online

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