Health
Screening for cervical cancer every 5 years can be as safe as every 3 years
Screening women with cervical cancer every five years instead of every three years can prevent many cancer cases, according to a new study.
Experts at King’s College London (KCL) have collected data from 1.3 million women in the United Kingdom. They found that screening women for traces of the human papillomavirus (HPV) found in 99% of all cervical cancers could safely extend the interval between tests.
The results were “very encouraging,” said Dr. Mateika Leboli, the lead author of the report.
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Currently, in the UK, women aged 25-49 are invited to a cervical examination every three years, and women aged 50-64 are invited every five years.
Dr. Rebolj said: “After the introduction of the HPV test for cervical screening, the 5-year interval is based on previous studies showing that it is at least as safe as the previous 3-year interval.
“Changing to a five-year screening means that we can prevent as many cancers as before, while allowing less screening.”
Prior to 2019, cytology tests (also known as smear tests) were the first to check for abnormalities in cervical cells, but now the samples taken during cervical screening are the first to be tested for HPV. To do.
According to the team, HPV infections occur before abnormal cells develop, so HPV tests detect more women at risk for cervical cancer.
Researchers at KCL, the University of Manchester, and the NHS will analyze data from the UK’s NHS Cervical Screening Program and track people who participated in the first two rounds of screening from 2013 to 2016 until the end of 2019. Followed up to.
They found that people under the age of 50 who were negative for HPV screening in the first round had a lower risk of detecting CIN3 + in the second round compared to cytopathological tests. Did.
The study found that 4.52 of 1,000 people after negative cytopathology detected CIN3 + in 1.21 of 1,000 people after negative HPV screening.
Dr. Rebolj said: “This monumental study relied on an interdisciplinary team, including the team from the NHS Cervical Screening Program in the United Kingdom, and worked with women being screened and their samples, as well as our academic partners.
“This partnership provides the most useful evidence for millions of women invited to screen throughout most of their adulthood.
“These promising results show that most women and people with the cervix do not need to be screened as often as they do today.”
Michelle Mitchell, Chief Executive Officer of Cancer Research UK, said:
“This is based on findings from years of research that show that the HPV test is more accurate in predicting who is at risk of developing cervical cancer compared to previous test methods.
“As changes to the screening program are made, they will be monitored to ensure that cervical screening is as effective as possible for everyone participating.
“It’s important to remember that screening is aimed at people who are asymptomatic. Therefore, if you notice any unusual changes, don’t wait for the screening invitation and talk to your doctor.”
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