Health
Studies have found that the cost of brand-name anticonvulsants increased by 277% between 2010 and 2018.
According to a study published online on June 15, 2022, the cost of branded epilepsy drugs increased by 277% between 2010 and 2018. Neurology®, American Academy of Neurology Medical Journal. The cost of generics for epilepsy decreased by 42% over the same period.
According to a study of Medicare people, branded medicines accounted for 79% of the cost of epilepsy drugs, but only 14% of tablets.
The cost of brand-name anticonvulsants has consistently increased since 2010, with the cost per pill skyrocketing, especially in addition to the increase in lacosamide prescriptions, and the cost of branded drugs is 10 times higher than generics. became. Previous studies have shown that medicines were the most expensive part of neurological treatment and anticonvulsants were the second most costly category of medicines prescribed by neurologists. increase. “
Samuel Waller Terman, MD, MS, Research Author, University of Michigan, and Member of the American Society of Neurology
In this study, researchers examined the records of a random sample of 20% of Medicare recipients between 2008 and 2018. There were 77,000 to 133,000 epilepsy patients each year.
Branded drug costs rose from $ 2,800 a year in 2008 to $ 10,700 a year in 2018, while generic drug costs fell from $ 800 to $ 460 in the meantime.
According to Tarman, the increase in prescriptions for the drug lacosamide accounted for 45% of the total increase in brand name costs.
Over time, the proportion of branded medicines in tablets decreased from 56% in 2008 to 14% in 2018. Terman said the decline in branded drug prescriptions is likely to correspond to the increased availability of common equivalents. He stated that the expiration of the lacosamide patent in March 2022 and other changes would affect prescribing patterns.
Many new drugs for epilepsy have been introduced in the last few decades. Doctors need to tailor their drug choices to the individual, and there is no single best drug. Many drugs for epilepsy can cause side effects such as cognitive impairment as well as interaction with other drugs.
The study found that the use of previously introduced first-generation drugs, called epilepsy drugs, and enzyme inducers with many drug interactions decreased between 2008 and 2018.
“Physicians need to consider social costs when deciding whether increasing the cost of branded medicines is worth the possible benefits,” Tarman said. “The new generation of drugs has potential benefits such as limited drug interactions and different side effect profiles, but there are conflicting studies on whether they are cost-effective.”
The limitation of the study was that it included only Medicare prescription claims. Therefore, the results may not apply to the young population of private insurance.
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