Study linked COVID to childhood detail syndrome

June 29-2020 About 300 children in 26 states fell into the mysterious COVID-related inflammatory condition between March and May. Six children died.

of the study This is the most detailed description of a disease called multisystem inflammatory syndrome, or MIS-C, in children. And they are giving pediatricians and parents a better idea of ​​what the condition will look like when it is struck.

The report depicts pictures of severely ill children and teens with at least four organ systems involved in the disease. 80% of children and adolescents in the study who were all under 21 years of age were treated in the intensive care unit and needed 20% Ventilation To help them breathe.

MIS-C differs from the serious course of COVID-19, which can endanger medically vulnerable children. MIS-C is a condition that is believed to occur days to weeks after previously healthy children fight off the virus that causes COVID-19.

The most common symptoms of MIS-C are Fever It lasts an average of 5 days. Over 90% reported some gastrointestinal symptoms- nausea,vomiting, diarrhea, Abdominal pain. Many children also had heart problems in response to the syndrome. artery Nourish the balloons of the heart. Most also had whole body markers inflammationSuch as high levels of C-reactive protein in blood.

There was evidence that more than two-thirds of the children in the study were exposed to COVID-19 because they were around a person who was known to have a positive blood test for the virus or was diagnosed with it. ..

Research published in New England Medical JournalIs a snapshot of the case, not the exact number.

“This is a minimum. We did not collect cases from all ICUs in the United States,” says Adrienne Randolph, MD, an emergency care specialist at Boston Children’s Hospital. She says 53 intensive care units provided data for the study.

“Our goal was only to show that it was seen across the United States,” says Randolph.

Nearly 100 of the cases detailed in the study came from New York State, which was the epicenter of New York State Coronavirus Pandemic In the usa

Secondly InvestigationResearchers from the New York Department of Health analyzed their cases. They conclude that MIS-C is clearly associated with COVID-19, with the peak of MIS-C cases following the peak of COVID-19 cases seen in New York one month later.

They say that about one-third of the affected children in New York Existing state, Most commonly obesity..

Syndromes share the characteristics of Kawasaki disease, A rare syndrome that attacks children after fighting an infectious disease. Kawasaki disease can also affect the heart, which often causes children to Skin rashSwollen red “strawberry tongue”; red, cracked lips; peel hands and feet; and red eyes. The main risk of Kawasaki disease is inflammation of blood vessels, especially those that pump blood to the heart.

In a New York study, researchers found that features of MIS-C that most closely resemble Kawasaki disease were more common in young children.

They also show that, like COVID-19, MIS-C affects New York blacks and Hispanic children more than whites and Asians. The New York analysis included data on races of 78 patients. 37% were white, 40% were black, 5% were Asian, and 18% were others. About one-third of ethnically-identified patients identified themselves as Hispanic.

If COVID-19 has spread to your area and your child has a fever, skin rash, or other strange symptoms, researchers say it is important to check in with a doctor ..

“It’s not very active so far, so it’s important to contact a pediatrician, especially this year,” Randolph says.

Early treatment is key to MIS-C and Kawasaki disease. Prolonged inflammation, if caught and not stopped, can lead to permanent heart damage.

Despite the collection of dreadful symptoms, Randolph says the syndrome is still rare and most children have recovered with treatment. “It’s encouraging,” she says.

Most of the study children were treated in the intensive care unit of the hospital. Over two-thirds received an intravenous administration of a purified blood product called immunoglobulin. This helps modify the body’s immune response. Other treatments included steroid And drugs that help to contract and raise blood vessels blood pressure.. Many needed temporary help to breathe from ventilators or ECMO devices.