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Studies show that women are more likely to suffer from Long COVID than men.




A new study published in a peer-reviewed journal today Current medical research and opinions, Women are more likely to suffer from Long COVID “significantly” than men, revealing that they experience substantially different symptoms.

Long COVID is a syndrome that has complications for more than 4 weeks, sometimes months, after the initial infection with COVID-19.

Researchers at the Johnson & Johnson office of the Chief Medical Officer Health of Women team, who analyzed data from approximately 1.3 million patients, found that women with Long COVID had a variety of symptoms, including ear, nose, and throat problems. Observed to show; disorders of mood, nerves, skin, gastrointestinal and rheumatism; as well as fatigue.

However, male patients were more likely to experience endocrine disorders such as diabetes and kidney disorders.

“Knowledge of the clinical manifestations of COVID-19, disease progression, and the underlying gender differences that underpin health outcomes includes both potential discriminatory treatment needs and sensitive and effective treatments. It is essential for the identification and rational design of public health interventions. Gender, “explains the author.

“Differences in immune system function between women and men can be an important factor in gender differences in Long COVID syndrome. Women can be protected from early infections and severity, faster and more powerful congenital and adaptation. It initiates a sexual immune response, but this same difference can make women more vulnerable to long-term autoimmune-related disorders. “

As part of the review, researchers will search for academic papers between December 2019 and August 2020 for COVID-19 and January 2020 to June 2021 for LongCOVID syndrome. Limited to those issued. The total sample size across the reviewed articles reached 1,393,355 unique individuals.

Although the number of participants may sound large, of the 640,634 articles in the literature, sufficient details on the symptoms and sequelae of COVID-19 disease to understand how women and men experience the disease. Only 35 provided gender data for.

The early onset of COVID-19 showed that female patients were much more likely to experience mood disorders such as depression, otolaryngology, musculoskeletal pain, and respiratory symptoms. Male patients, on the other hand, were more likely to suffer from kidney damage-; those that affect the kidneys.

The authors state that this integration of the available literature is one of the few to analyze the specific health status that results from gender-based COVID-related illnesses. Many studies have examined gender differences in hospitalization, ICU admission, ventilation support, and mortality. However, studies of the specific conditions caused by the virus and their long-term damage to the body have not been fully studied in terms of sex.

“Gender differences in results have been reported during previous coronavirus outbreaks,” the author adds. “Therefore, we may have expected differences in results between women and men infected with SARS-CoV-2. Unfortunately, most studies did not evaluate or report detailed gender data, so treatment. Gender-specific clinical insights that could affect the research were limited. ”Ideally, gender data should be available even if it is not the researcher’s primary purpose. .. That way, other interested researchers can use the data to look for important differences between genders.

The paper also mentions complex factors that deserve additional research. Women may be at increased risk of being exposed to the virus, especially in certain occupations such as nursing and education. “There is a disparity in access to care by gender, which can affect the natural history of the disease and lead to more complications and sequelae.”

The latter acts as a rallying cry. The availability of gender data and intentional analysis is essential to address different outcomes in the course of the disease. The survey will not be completed unless the data is made available to those who want to answer the question of gender and gender is important.


Journal reference:

Sylvester, SV, et al. (2022) Gender differences between the sequelae of COVID-19 infection and long COVID syndrome: review. Current medical research and opinions.




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