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Young patients with comorbidities were at increased risk of death during the first COVID-19 wave, the study found.

Young patients with comorbidities were at increased risk of death during the first COVID-19 wave, the study found.


Researchers at Sirgangalam Hospital in Delhi conducted a retrospective study in which young patients with underlying comorbidities were initially more severe with COVID-19 compared to older patients with similar underlying conditions. And a wave of coronavirus pandemics in India that proved to have a relatively high risk of mortality. The results of this study were published in Springer Nature’s Molecular and Cellular Biochemistry on Saturday.

During the study, researchers admitted 2586 COVIDs from April 8, 2020 to October 4, 2020 to observe the association between diabetes (DM), hypertension (HT) and chronic kidney. -19 Analysis of inpatient data Diseases related to prognosis and mortality of COVID-19 infection in inpatients (CKD).

“Our study also found that women had a relatively high risk of death compared to men with the same comorbidities, except for hypertensive patients,” said the author and consultant of the research division at Sirgangaram Hospital. Dr. Rashmirana said in a statement. ..

Researchers reported that of the 2586 patients, 779 (30.1%) needed to be admitted to the ICU, while 1807 (69.9%) were not admitted to the ICU. Of the 2586 inpatients with COVID-19 infection, 2269 (87.7%) had a mortality rate of 317 (12.3%).

“Studies show that the risk of COVID-19 infection severity in young patients with an underlying disorder is relatively high in disease severity and mortality risk compared to older patients with a similar underlying disorder. “I see,” said Ranjan, co-author and chair of the blood transfusion department at Dr. Vivek’s Sagangalam Hospital.

Meanwhile, Dr. Atul Gogia, a co-author and senior consultant at the School of Medicine, found in their study that patients with chronic kidney disease have a higher rate of disease progression, complications, and mortality, following hypertension and diabetes. I made it clear.

“Comparing the effects of multiple comorbidities with the severity of COVID-19 infection, we found that the presence of comorbidities increased the risk of admission to the ICU. As the number of comorbidities increased, the severity of COVID-19 infections increased. The risk of the disease is also significantly increased, “said Dr. DSRana, co-author and chair of the Department of Renal Science.

The study also found that the presence of comorbidity poses a greater risk of admission to the ICU. In addition, patients with diabetes and hypertension were associated with a longer recovery period. As the number of comorbidities increases, so does the risk of severity of COVID-19 infection.




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