Connect with us


Estimating Hidden Deafness | Harvard Medical School




Researchers at Mass Eye and Ear have developed a word-score model that can estimate the amount of deafness hidden in the human ear.

In a new study published on June 23 Scientific Reports, A team of researchers at Harvard Medical School at Massachusetts Eye and Years Eaton Peabody Laboratories determined an average voice score as a function of age from approximately 96,000 ear records examined by Mass Eye and Year.

The data were then compared to a previous study at Mass Eye and Ear, which tracked the mean loss of cochlear nerve fibers as a function of age. By combining both datasets, researchers constructed estimates of the relationship between people’s speech scores and neural survival.

Get more HMS news here

According to the principal investigator Stephen HouseThis new model, an HMS associate professor of otolaryngology head and neck surgery and a senior researcher at Mass Eye and Ear’s Eaton-Peabody Laboratories, provides a better assessment of patients’ cochlear nerve injury and associated speech intelligibility disorders. be connected. Nerve loss. This model also provides a way to estimate the effectiveness of deafness interventions, such as the use of personal sound amplification products and hearing aids.

“Before this study, we were able to use a long test battery to estimate nerve loss in living patients or measure cochlear nerve damage by removing the temporal bone at the time of death,” the Maison said. I am saying. “It is now possible to estimate the number of nerve fibers missing in the human ear using the same normal voice scores from hearing tests collected in clinics around the world.”

Reveal hidden deafness

Two main factors determine how well a person hears: audibility and comprehension. Hair cells, the sensory cells in the inner ear, contribute to the audibility of sound, the size needed to be able to detect it. When hair cells receive sound, they pass electrical signals to the cochlear nerve, which in turn passes those signals to the brain. How well the cochlear nerve relays these signals contributes to the clarity or intelligibility of the sounds processed within the central nervous system.

For years, scientists and clinicians have believed that hair cell deterioration is a major cause of deafness, and that cochlear nerve damage is widespread only after hair cell destruction. Audiograms, long considered the gold standard for hearing tests, provide information on hair cell health. Because nerve loss was thought to be secondary to hair cell loss or dysfunction, patients with normal audiograms were given a clean health bill, despite reports of hearing impairment in noisy environments. Was done. Experts understand why audiograms do not assess auditory nerve health.

“This explains why some patients who report difficulty understanding conversations in busy bars and restaurants undergo a” normal “hearing test. Similarly, it explains why many hearing aid users who receive amplified sound still struggle with audio intelligibility, “says the Maison.

In 2009, M. Charles RivermanProfessor Harold F. Schknecht of HMS Otology and Laryngology, and Sharon KujawaHMS Professor of Otorhinolaryngology Head and Neck Surgery, a senior researcher at the Eaton Peabody Institute, overturned scientists’ thinking about hearing when they discovered hidden deafness. Their findings reveal that cochlear nerve damage precedes hair cell loss as a result of aging and noise exposure, and by not providing information about the cochlear nerve, audiograms actually reach the ear. It suggested that the full extent of the damage was not assessed.

Building a model for predicting cochlear nerve injury

In this study, the Maison and his team used a speech intelligibility curve to predict an individual’s speech score based on audiograms. Next, we measured the difference between the predicted word recognition score and the score obtained during the patient’s hearing assessment.

The Maison explained that the difference between the predicted score and the measured score reflects a lack of intelligibility, as the list of words was presented at a level well above the patient’s hearing threshold (audibility is not an issue).

After considering many factors, including cognitive impairment that may be associated with aging, researchers argued that the magnitude of these discrepancies reflected the amount of cochlear nerve damage or hidden deafness. .. Next, we applied measurements of nerve loss from existing histopathological data from the human temporal bone to build a predictive model based on standard hearing tests.

The findings confirmed an association between lower speech scores and more cochlear nerve injury. For example, the worst score was found in patients with Meniere’s disease. This is consistent with studies of the temporal bone showing a dramatic loss of cochlear nerve fibers. On the other hand, patients with conductive and drug-induced and normal age-related hearing loss (the patients with the least amount of cochlear nerve injury) showed only moderate or slight differences.

Changing the Perspective of Hidden Deafness Research

According to the World Health Organization, more than 1.5 billion people live with some degree of deafness. Some of these individuals may not be eligible for traditional hearing aids, especially if they have mild to moderate high frequency deafness. Knowing the extent of nerve damage should inform the clinician of the best way to address the patient’s communication needs and provide appropriate intervention other than the use of effective communication strategies.

By identifying which patients are most likely to have more cochlear nerve injuries, Maison said this model will help clinicians assess the effectiveness of traditional and new sound amplification products. thinking about. Researchers also want to introduce a new hearing test protocol to further refine the model and provide better intervention by assessing word performance scores in a noisy environment rather than a quiet environment. ..

Co-authors of this study include Kelsie J. Grant, Aravindakshan Parthasarathy, Viacheslav Vasilkov, Benjamin Caswell-Midwinter, Maria E. Freitas, Daniel B. Polley, M. Includes Charles Liberman and Victor De Gruttola.

This study was supported by the National Institute of Health (NIDCD P50-DC015857).

Revised from the news release of Mass Eye and Year.




The mention sources can contact us to remove/changing this article

What Are The Main Benefits Of Comparing Car Insurance Quotes Online

LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos


to request, modification Contact us at Here or [email protected]