Health
Fauci says he is experiencing a COVID rebound
Dr. Anthony Fauci, the federal government’s premier infectious disease expert, says he is experiencing a mysterious phenomenon known as the “COVID rebound” associated with oral treatment Paxrovid.
What you need to know
- Dr. Anthony Fauci, the federal government’s premier infectious disease expert, says he is experiencing a mysterious phenomenon known as the “COVID rebound” associated with oral treatment Paxrovid.
- On June 15, the National Institute of Health announced that Fauci, director of the National Institute of Allergic Infectious Diseases and chief medical adviser to President Joe Biden, had tested positive for COVID-19.
- During a remote interview with the Foreign Policy Global Health Forum on Tuesday, an 81-year-old doctor revealed his setbacks and said he had begun taking Pax Rovid’s second course.
- The CDC has issued a health recommendation on “possible recurrence of COVID-19,” but authorities continue to recommend this drug for the initial treatment of mild to moderate COVID.
According to the Center for Disease Control and Prevention, recurrence of COVID-19 symptoms, or new positive tests after a negative test, are reported 2-8 days after the patient first recovers from the coronavirus after treatment with Paxrovid.
On June 15, the National Institute of Health announced Forch, director of the National Institute of Allergic Infectious Diseases and Chief Medical Advisor to President Joe Biden. COVID-19 test positive..
During a remote interview with the Foreign Policy Global Health Forum on Tuesday, an 81-year-old doctor revealed his setbacks and said he had begun taking Pax Rovid’s second course.
Fauci said he had recovered from the first attack from the virus, tested negative for three days, and then tested positive again on the fourth day of last week.
“And the next day or so, I started feeling much worse than the first go-around,” Forch said on Tuesday. “So I went back to Paxlovid, and now I’m on the fourth day of the five-day course.
“Fortunately, I feel pretty good,” he added. “That is, I’m not perfect in the absence of symptoms, but I certainly don’t feel any serious illness.”
Developed by Pfizer and licensed by the Food and Drug Administration in December 2021, Paxrovid is administered to unhospitalized symptomatic patients at risk of developing serious illness.
The single dose of Paxlovid is actually 3 tablets. Two 150 mg tablets of Nirmatrelvir and one 100 mg tablet of ritonavir. Nilmatrelvir is designed to block the enzymes that the coronavirus needs to replicate, while ritonavir slows the breakdown of nirmatrelvir, allowing it to remain active in the body longer.
Pfizer clinical trials have shown that taking it within 3 days of onset of symptoms has an 89% effect on hospitalization and death, and an 88% effect within 5 days.
But in May, the CDC issued Health advisory About “possibility of recurrence of COVID-19”. Authorities said the recurrence could be part of the natural history of SARS-CoV-2 (a virus that causes COVID-19) infection in some people, regardless of vaccination status, regardless of treatment with Paxrovid. There is sex. “
The CDC said there were no reports that COVID rebounds would lead to serious illness. He also states that there is no evidence that people who have relapsed symptoms or who test positive are in need of an additional course of Paxrovid.
That is also rare. Discovered by Mayo Clinic researchers Less than 1% of patients at high risk for severe COVID-19 treated with Paxlovid experienced a second seizure.
“Paxlobid continues to be recommended for the initial treatment of mild to moderate COVID-19 among people at high risk of progression to severe disease,” said the May CDC Advisory.
Health officials say those who have experienced a COVID rebound will need to be quarantined again for at least five days.
A study conducted by researchers at the University of California, San Diego, published last week. Journal Clinical Infectious DiseasesWe evaluated one patient with COVID rebound and confirmed that recurrence was not associated with a virus that developed resistance to treatment. Scientists instead believe that it is the result of inadequate exposure to Paxrovid. This suggested that it may be related to drugs that are metabolized more rapidly in some people, or that need to be delivered over a longer period of time.
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