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LSU Health’s New Orleans Lab states that it has discovered two new Omicron subvariants.




New Orleans (WVUE)-LSU Health Researchers at the New Orleans Institute for Precision Medicine said on Tuesday (July 5) that two previously unknown submutations of the highly contagious COVID-19 Omicron variant He said he had identified his body.

“As far as we know, these Omicron subvariants have never been reported in the United States,” said Dr. Lucio Mille, co-director of the lab and director of genetics at LSU Health New Orleans School of Medicine. increase. “The potential clinical and public health implications of them are still unknown.”

The laboratory said it has identified two new SARS-CoV-2 mutants in Louisiana. This is a sub-mutant of the Omicron variant that has caused the latest surge in coronavirus cases in the state. The new subvariants have been designated BE.1 and BF.1. LSU Labs has partnered with the Louisiana Health Department, Oxner Health, and Louisiana Infectious Disease Bioinformatics Company BIE to collect samples from the COVID-19 test, examine their gene sequences, and make them epidemic in the state. Identify the version of the disease you have.

“The pattern that emerges from the data is that the emergence of dominant mutations such as deltas and omicrons temporarily reduces the genetic diversity of the virus as new mutations take over,” Miele said. “Then, multiple submutations emerge from the dominant mutation mutation.

“This is the most important time to monitor the emergence of new subvariants and determine their differences, especially when their numbers begin to increase. This type of information is transmitted to treatment or It’s important to understand resistance. “

According to Miele, known variants of SARS-CoV-2 are becoming more widespread and able to evade immunity. Omicron is more contagious than Delta, and Omicron subvariants BA.4 and BA.5 appear to be capable of infecting people who were immune to previous variants and subvariants. Some have shown resistance to monoclonal antibodies used to reduce the severity of COVID-19 infection.

“We monitor these new subvariants and compare their experience with other centers to determine how these variants occurred and if they were widespread,” Miele said. Told.

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