Health
The Covid virus continues to evolve. Why aren’t you vaccinated?
March 16 First volunteer in 2020 I received a shot Only 63 days after the company created the genetic blueprint for the new virus, Moderna’s then- Covid-19 vaccine was developed. But Moderna’s rivals have beaten the market. Pfizer’s Covid vaccine was approved for use in the United States in less than a year with record results. Previously, the fastest vaccine ever developed was for mumps, which took about four years.
The speed at which both companies were able to provide vaccines mRNA technology.. Instead of using the virus itself to boost the immune response as in older vaccines, scientists instead use a programmable genetic code called mRNA to boost the immune response. mRNA tells the body to make different spike protein versions of the coronavirus, so it can make antibodies that neutralize that spike. Although mRNA is quickly degraded, the memory of peplomer remains in the immune system, ready to launch an attack if it is attacked again.
The promise of mRNA technology Its adaptability.. Vaccine makers have advertised their plug-and-play nature. If the virus mutates and circumvents the current vaccine, scientists only need to replace the new mRNA to match the new version of the virus.But today, despite a wave of variants including: delta, Omicron, And the latest threats (Omicron subvariants BA.4 and BA.5), the Covid-19 vaccine and booster shots target the original virus identified in late 2019. Why didn’t the variant-specific boosters arrive early?
“You are dealing with a rapidly mutating virus. Each of these variants has been around for several months and is then replaced by a new variant,” said Archana Chatterjee, an infectious disease specialist, at Chicago Medical College. The director says. “This is a race we are constantly lagging behind.”
And BA.4 and BA.5 are the fastest movers ever. “The virus has become more and more contagious over the last two years,” said Chatterjee, a member of the Vaccine and Related Bioproducts Advisory Board (VRBPAC), an independent expert board that advises the United States. continue. Food and Drug Administration.
Currently available vaccines have significantly reduced Covid-19 deaths and hospitalizations, but “their efficacy seems to diminish over time,” said the director of the FDA’s Center for Biologics Evaluation and Research. One Peter Marks said: June 28 VR BPAC meeting.. The first booster shots helped restore some protection against severe illness, but the effect seems to be diminishing.
In June, due to all these factors, VRBPAC recommended that vaccine manufacturers update their Fall / Winter 2022 Covid booster shots and tune them for the BA.4 and BA.5 subvariants. Chatterjee says the Commission has made recommendations based on evidence that these subvariants appear to be driving a new wave of hospitalization across the United States and the United Kingdom. The US government plans to purchase millions of variant-specific doses for the fall booster campaign.
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