Health
British scientists have taken a “promising” step towards a single Covid and cold vaccine | Coronavirus
Scientists have made “promising” advances towards developing a universal coronavirus vaccine to combat the common cold with Covid-19.
Researchers at the Francis Crick Institute in London found that certain regions of the Sars-CoV-2 peaplomer (the virus that causes Covid-19) are all Covid-19 variants and common colds.
Developing vaccines that protect against various coronaviruses is a major challenge, they said. Because there are many important differences in this viral family, they mutate frequently and generally induce incomplete protection against reinfection. As a result, people can suffer from common colds repeatedly and can be infected multiple times with different variants of Sars-CoV-2.
Scientists say that universal coronavirus vaccines need to trigger antibodies that recognize and neutralize various coronaviruses and prevent the virus from invading and replicating host cells.
In a new study, researchers investigated whether antibodies targeting the “S2 subunit” of the Sars-CoV-2 peaplomer also neutralize other coronaviruses. After vaccination of mice with Sars-CoV-2 S2, researchers found that mice produced antibodies that could neutralize many other animal and human coronaviruses.
They include the common cold coronavirus HCoV-OC43, the original strain of Sars-CoV-2, the D614G mutant that prevailed in the first wave, alpha, beta, delta, the original omicron, and two bat coronas. It contained a virus. The findings are published in the journal Science Translational Medicine.
“The S2 region of the peplomer is much more similar to the various coronaviruses than the S1 region, making it a promising target for potential pan-coronavirus vaccines,” said Francis Crick, co-lead author of the study. Kevin Ng said. Laboratory. “Vaccines targeting this area should be more potent because they are less susceptible to mutations.”
So far, the S2 region of peplomer has been overlooked as a potential basis for vaccination, the researchers said.
George Kassiotis, the corresponding author and key group leader of the Francis Crick Institute, said:
“This is different from vaccines that target the more volatile S1 region. Vaccines are effective against the corresponding mutants designed, but against other mutants and a wide range of coronaviruses. It cannot be targeted.
“There is still a lot of work to be done to continue testing S2 antibodies against various coronaviruses and to find the best route to design and test potential vaccines.”
Researchers will continue to study the potential of pancoronaviruses that target the S2 region of peplomers and how they can integrate with currently approved vaccines.
Sign up for our free daily newsletter, First Edition – 7am BST on weekdays
Nikhil Faulkner, also co-lead author of the Francis Crick Institute, said:
“This provides sufficient protection to withstand the initial infection, during which time the immunity specific to a particular virus may develop further.”
Professor Pennyward, a visiting professor of pharmaceutical medicine at Kings College London, who was not involved in the study, said that the universal coronavirus vaccine “can solve the problem of an endless wave of new diseases caused by mutants with reduced vaccine sensitivity. “.
|
Sources 2/ https://www.theguardian.com/world/2022/jul/27/uk-scientists-take-promising-step-towards-single-covid-and-cold-vaccine The mention sources can contact us to remove/changing this article |
What Are The Main Benefits Of Comparing Car Insurance Quotes Online
LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos
to request, modification Contact us at Here or [email protected]
 |
 |
 |
