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CDC: Increased blood clots, kidney failure in children after COVID

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In the year following COVID-19 infection, children and adolescents developed a range of symptoms and conditions, but no mental or respiratory problems, according to a CDC study.

Compared with their peers who had not been diagnosed with COVID-19, adolescents aged 0–17 years with laboratory-confirmed disease were significantly more likely to develop the following conditions within 31–365 days after diagnosis: .

  • Acute pulmonary embolism (adjusted HR 2.01, 95% CI 1.62-2.50)
  • Myocarditis and cardiomyopathy (adjusted HR 1.99, 95% CI 1.81-2.19)
  • Venous thromboembolic events (adjusted HR 1.87, 95% CI 1.54-2.26)
  • Acute and unspecified renal failure (adjusted HR 1.32, 95% CI 1.22-1.43)
  • Type 1 diabetes (adjusted HR 1.23, 1.13-1.33)

Also associated with COVID-19 were persistent arrhythmias, bleeding disorders, smell and taste disturbances, malaise and fatigue.

Nevertheless, Dr. Lyudmyla Kompaniyets, a health economist at the CDC in Atlanta, and Weekly reports of morbidity and mortality.

The study authors Diabetes Myocarditis in children months after COVID is consistent with previous evidence, but other observed risks appear new in this population.

especially, COVID patient There were lower rates of respiratory, mental health, neurological, muscular, and sleep disturbances compared with the general population in this study.

“The reason for these observed associations is likely multifactorial, with patients uninfected with COVID-19 having health care experiences that may be related to COVID-19. It may be because they were selected from a cohort of patients and were in lesser health than they had previously been. Patients with COVID-19 At baseline,” suggested the CDC group.

The definition of post-COVID symptoms and conditions used by the authors was new, recurrent, or ongoing health problems that occurred >4 weeks after infection with SARS-CoV-2.

This study was conducted using a large medical claims database and evaluated 9 potential post-COVID signs and symptoms and 15 potential post-COVID conditions in children and adolescents.

Data were collected on 781,419 US COVID-19 children and adolescents who did not report COVID-19 but had no reported COVID-19 infection from March 2021 to January 2022 . Up to 365 days.

The cohort had a mean age of 12 years and was split equally between boys and girls.

Statistical models were adjusted for age, gender, race, US Census Bureau region, payer type, prior medical complexity, and prior hospitalization.

Kompaniyets and colleagues cautioned that analyzes of post-COVID symptoms and conditions are subject to misclassification bias and do not account for events that began before COVID infection. It was unclear whether the reported symptoms were transient or chronic.

Some children may also have undocumented COVID-19, they acknowledged, and with 70% of patients receiving Medicaid-controlled care, all children and Generalization of the study to adolescents is limited, he added.

Finally, vaccination status was not adjusted in the study due to the assumed underreporting in the dataset. Nonetheless, the CDC group maintained the importance of COVID vaccination in children and teenagers.

“COVID-19 Prevention Strategies Including Vaccination All subjects over 6 monthsare important for preventing SARS-CoV-2 infection and subsequent illness and for mitigating the public health impact of post-COVID symptoms and conditions,” they wrote.

  • author['full_name']

    James Lopilato Staff writer for Medpage Today. He covers a variety of topics being explored in current medical research.

Disclosure

Kompaniyets reports no conflicts of interest.

Sources

1/ https://Google.com/

2/ https://www.medpagetoday.com/nephrology/generalnephrology/100099

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