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Sleep apnea increases risk of cancer, dementia and blood clots

Sleep apnea increases risk of cancer, dementia and blood clots

 


September 6, 2022 – Those who have obstructive sleep apnea It may increase the risk of cancer, dementia, and dangerous blood clots, according to. new research It was presented at the 2022 International Congress of the European Respiratory Society in Barcelona on Monday.

In people with obstructive sleep apnea (OSA), part or all of the airway becomes blocked during sleep, interrupting breathing several times a night.This can lead to loud snore, gasping, fatigue during the day.of Sleeping disorder Affecting 7% to 13% of people, those at greatest risk are: Overweight or obesity, diabetes, smoking, or heavy drinking alcohol.

“Although we already know that patients with obstructive sleep apnea have an increased risk of cancer, it is not clear whether this is due to OSA itself or related cancer risk factors. . obesitycardiometabolic diseases and lifestyle factors,” said Andreas Palm, MD, a researcher and senior consultant at Uppsala University, Sweden, who published one of the studies. in a statement.

“Our findings indicate that OSA-induced oxygen deprivation is independently associated with cancer.

Palm and colleagues looked at data from about 63,000 patients in Sweden about five years before beginning treatment for obstructive sleep apnea. Between 2010 and 2018, patients continuous positive airway pressure, keeps the airways open during sleep. The researchers linked this information with data from the Swedish National Cancer Registry and social and economic data from Statistics Sweden.

The researchers matched a control group of about 2,000 patients with sleep apnea diagnosed with cancer to a control group of 2,000 patients with sleep apnea but not cancer. . They found that cancer patients had more severe sleep apnea, and oxygen levels were lower in lung, prostate, and lung cancer patients. melanoma.

“The results of this study highlight the need to consider untreated sleep apnea as a cancer risk factor and the need for physicians to be aware of the potential for cancer when treating patients with OSA. I do,” said the researcher. “However, extending cancer screening to all her OSA patients is not justified or recommended by our findings.”

Another study presented at the conference found that obstructive sleep apnea was also associated with a significant decline in mental strength, especially among men and people over the age of 74.

Swiss researchers studied 350 people over the age of 65 who underwent sleep studies between 2003 and 2008 and had follow-up appointments every five years. Cognitive assessments were performed during the first follow-up from 2009 to 2013 and his 5-year follow-up to assess brain function, processing speed, Executive functionverbal memory, language, and visual perception of spatial relationships between objects.

The research team found that obstructive sleep apnea was associated with significant declines in brain function, processing speed, executive function, and verbal memory. Low oxygen levels during sleep had the greatest effect.

“This study shows that the severity of sleep apnea and nocturnal oxygen deprivation contribute to cognitive decline in older adults,” said researchers at the Research Center for Sleep at the University of Lausanne, Switzerland. Nicola Marchi, M.D., Ph.D. presentation.

In a third study conducted in France, patients with severe obstructive sleep apnea Venous thromboembolismor dangerous blood clots that form in the lower extremities, thighs, or pelvis and can cause a heart attack or stroke.

Researchers studied 7,355 patients who were followed for more than six years, including 104 who developed blood clots. Those who spent more than 6% of her sleep with oxygen levels below 90% were twice as likely to develop blood clots as those who were not deprived of oxygen.

“These three studies anxiety Winfried Randerath, MD, head of the Sleep Disordered Breathing Group of the European Respiratory Society and professor at the University of Cologne, Germany, said in a statement.

“People should be aware of these links and try to make lifestyle changes to reduce their risk of OSA. For example, healthy weight“We look forward to further research that may help clarify whether OSA may be causing some of the health problems seen in these studies,” he said.

Sources

1/ https://Google.com/

2/ https://www.webmd.com/sleep-disorders/news/20220906/sleep-apnea-linked-higher-risks-cancer-dementia-clots

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