Health
‘Not the same as the flu’: Covid-19 directly damages DNA in heart tissue, experts find.read here
Covid-19 infection damages heart tissue, researchers have found.The finding will help experts formulate better treatments for the condition.Study published in the journal Immunology . The study used real heart tissue collected during autopsy from seven Covid-19 patients, two who died of influenza, and six control patients in Brazil.
The research Covid-19 damaged DNA in heart tissue, was not detected in influenza samples. Notably, the researchers also found that Covid-19 and influenza, both severe respiratory viruses, appear to have very different effects on heart tissue.
“Compared to the 2009 influenza pandemic, Covid caused more severe and long-lasting cardiovascular disease, but what caused it at the molecular level,” said Artha Krasinge of the University of Queensland, Australia. I didn’t know.
“While our study failed to detect viral particles in the heart tissue of Covid-19 patients, we did find tissue changes associated with DNA damage and repair.
As DNA damage and repair mechanisms are linked to chronic diseases such as diabetes, cancer, atherosclerosis and neurodegenerative diseases, understanding why this is happening in Covid-19 patients is important. Researchers say it’s important.
Data related to the cardiac effects of Covid-19 were previously limited to blood biomarkers and physiological measurements due to the invasiveness of obtaining cardiac biopsy samples.
The findings provided insight into how Covid-19 impacted the body compared to other respiratory viruses.
Professor John Fraser, founder of the international Covid-19 Critical Care Consortium, said: “We looked at heart tissue samples from the flu and found that it caused excessive inflammation.
“Whereas we found that Covid-19 attacks the DNA of the heart, perhaps directly rather than as a knock-on from inflammation,” Fraser said.
The study highlights that the two viruses appear to have very different effects on heart tissue, something researchers hope to better understand in larger cohort studies.
“What we have made clear is that Covid is not ‘like the flu,'” said Fraser.
“This study helps us understand how Covid-19 affects that heart. It’s the first step in finding the best treatments to repair the heart.
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