Connect with us

Health

PCOS can present differently based on geographic region, study finds

PCOS can present differently based on geographic region, study finds

 


Analysis of data from over 1600 women Polycystic Ovarian Syndrome (PCOS) provides insights into regional variations in hormonal and metabolic parameters for disease across the United States.

The results of this study, which compared data from black and white women with PCOS from Alabama and California, showed many similarities between races, although Alabama women had excessive They were more likely to have hair growth and insulin resistance, and California women had excessive hair growth and insulin resistance. Your testosterone levels are more likely to rise.

“In our study, we found geographic differences in PCOS between black and white women, which suggests that there are both genetic and environmental influences on how the disease presents.” ,” said Margareta D. Pisarska, MD of Cedars-Sinai, Los Angeles, California. in a statement“Continued research is needed to identify race- and ethnicity-specific modifiable risk factors for PCOS to bring precision medicine to the management of this disease.”

The study, funded by the National Institutes of Health and the Helping Hand of Los Angeles Inc., was conducted by Pisarska and colleagues because of the lack of reliable information related to geographical differences in PCOS symptoms. it was done. With this in mind, the researchers leveraged data from 1,610 women who were treated in tertiary care-based specialty clinics in Alabama and California from 1987 until 2010, using prospective We designed a cohort study.

The primary outcome measures of interest in this study were demographic data, menstrual cycle history, hormonal and metabolic parameters. This information was obtained through participant interviews, physical examinations, and laboratory studies. Metabolic parameters of interest include BMI, waist-to-hip ratio (WHR), glucose tolerance test, and HOMA-IR score.

The analysis suggested that Alabama women with PCOS were younger and had a higher BMI than California women.In an analysis adjusted for age and BMI, Alabama women with PCOS were more likely to have hirsutism (adjusted odds ratio [aOR]1.8 [95% CI, 1.4-2.4]; P. <.001) higher HOMA-IR score (adjusted beta coefficient, 3.6 [95% CI, 1.61-5.5]; P. <.001). Further analysis suggested that women with her PCOIS from California were more likely to be hyperandrogenic than their Alabama counterparts (free testosterone aOR, 0.14; 95% CI, 0.11 -0.18; P. < 0.001; total testosterone aOR, 0.41. 95% CI, 0.33–0.51).

The investigators noted that these results were consistent even when stratified by race for whites. Although shown not to differ by location, differences in androgen profiles and metabolic dysfunctions based on region persisted.

“Having confirmed that there are geo-epidemiological differences, we intend to conduct follow-up studies comparing black and white women with PCOS and adjusting for geo-epidemiological differences,” Pisarska added. “Furthermore, we seek to examine the factors contributing to these differences in order to tailor treatment based on specific needs to improve care for all PCOS women.”

This studyRegional variation in hormonal and metabolic parameters in white and black women with PCOS in the United Stateswas published in Journal of Clinical Endocrinology and Metabolism.

Sources

1/ https://Google.com/

2/ https://www.endocrinologynetwork.com/view/pcos-can-present-differently-based-on-geographic-region-study-finds

The mention sources can contact us to remove/changing this article

What Are The Main Benefits Of Comparing Car Insurance Quotes Online

LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos

ExBUlletin

to request, modification Contact us at Here or [email protected]