Health
Detects signs of dementia 9 years before symptoms
- Researchers say it may be possible to diagnose dementia nine years before symptoms appear.
- They say falls, balance, and problem-solving problems may be early signs of dementia.
- Experts say early diagnosis is important because it gives people the chance to start treatment early and participate in clinical trials.
Signs of many diseases associated with dementia can be detected up to 9 years before diagnosis.
according to it
Researchers from the University of Cambridge and the Cambridge University Hospitals NHS Foundation Trust in the UK UK Biobank.
Findings include:
- people who developed Alzheimer’s disease were more likely to have fallen in the last 12 months.
- who developed progressive supranuclear palsyaffecting balance, was more than twice as likely for others to fall.
- People who developed dementia-related illness tended to have reduced problem-solving and number recall skills.
The scientists noted that participants had worse overall health at baseline for all conditions studied, including Alzheimer’s disease. Parkinson’s diseaseWhen Dementia with Lewy bodies.
According to one paper, falls may be a sign of cognitive impairment. 2021 study published in Frontiers in Neuroscience.
“Falls can be associated with a variety of orthopedic or brain problems,” said Dr. Douglas CharcléProfessor of Clinical Neurology and Psychiatry, Ohio State University School of Medicine.
“Balance and gait disturbances due to degenerative disease and stroke are very common,” Scharre told Healthline. “Falls are correlated with the development of dementia. , which may indicate a disturbance in the balance area, which should indicate the need to look for causes that can be prevented or treated.”
Few treatments are currently available dementia and other neurodegenerative diseases. Medical professionals usually diagnose these conditions only after symptoms appear. However, disease progression may have begun years or decades before symptoms began.
“Reviewing the patient’s medical history revealed that he had exhibited some form of cognitive impairment years before symptoms became apparent and prompted the diagnosis.” Nor Swadiudipong“The impairment was often subtle, but it spanned several facets of cognition,” said study author and junior physician at the University of Cambridge.
By the time of diagnosis, it is often too late to change the disease course or enroll in clinical trials.
“With degenerative disease, which is a progressive condition, it is not surprising to see cognitive and functional decline before diagnosis,” said Scharre. “We are not doing enough to diagnose patients in the early stages of these diseases.”
“It is recommended cognitive test It’s about taking a baseline and tracking it over time to see changes in individual patients and catch changes early,” Scharre continued. “Early identification of cognitive changes could increase access to disease-modifying treatments and lead to better outcomes.”
Early diagnosis also helps identify people who can participate in research looking for potential new treatments.
“The problem with clinical trials is that they often recruit diagnosed patients on an as-needed basis, but we know that by this point the patient has already moved on and there is no stopping the patient’s condition. I know.” Tim LittmanPhD, senior clinical research fellow and senior study author in the Department of Clinical Neuroscience at the University of Cambridge, said in a press statement. more likely to be confirmed.”
Other early signs of Alzheimer’s disease, according to Alzheimer’s Associationinclude:
- Memory impairment that interferes with daily life
- Difficulty planning and problem solving
- Difficulty completing familiar tasks
- confusion of time and place
- Inability to understand visual images and spatial relationships
- New problems with words when speaking and writing
- Can’t find items or follow steps
- Impaired or diminished judgment
- Withdrawal from work and social activities
- changes in mood or personality
See your doctor if you or someone you love has these symptoms. It can be hard to start a conversation, but experts say early detection and diagnosis can help treat it.
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