New Omicron Subspecies The White House warned this week that HIV patients, kidney transplant recipients, and other immunocompromised people are resistant to major antibody treatments, making them particularly vulnerable to Covid this winter.
Dr. Ashish Jha, White House Covid chief, said, “With some new variants emerging, some of the major tools we had to protect immune-compromised people like Evusheld. may not work, and that is a big challenge, the task force told reporters on Tuesday.
On Tuesday, President Joe Biden warned the adults who have weakened the immune systems of an estimated 7 million people in the United States. particularly at riskbut he could offer little reassurance beyond telling him to talk to his doctor about what precautions he should take.
“new variant The president said some of the existing precautions may be ineffective for immunocompromised people before receiving boosters on Tuesday. We strongly recommend that you take precautions. “
The message conflicts with the White House’s repeated assurances that the US will have all the vaccines and treatments it needs to fight Covid this winter. Expect further surge.
This may be true for the general public, but not for those with weak immune systems. They include cancer patients, organ transplant recipients, HIV-infected people, and people taking drugs for autoimmune diseases.
Evusheld is an antibody cocktail approved by the Food and Drug Administration to prevent Covid in people over the age of 12 with moderately or severely compromised immune systems. This drug is given to him as two injections every six months before infection.
Evsheld AstraZenecahas helped bridge the defense gap in people with weak immune systems who are unable to mount a strong response to vaccines. Camille Cotten, an infectious disease expert who specializes in treating people with weak immune systems The drug and several doses of vaccination have significantly reduced hospitalizations in this cohort in the past few months, according to the WHO.
Cotton, a physician at Massachusetts General Hospital and an independent agency member of the Centers for Disease Control and Prevention, said: Vaccine Advisory Board.
However, the more immunoevasive omicron subvariants such as BA.4.6, BA.2.75.2, BF.7, BQ.1 and BQ.1.1 are resistant to Evusheld. According to the National Institutes of HealthFor example, scientists at Columbia University found that Evusheld completely ineffective Against BA.4.6.
Also, BQ.1 and BQ.1.1 are likely to be resistant to bebuterobimab, Eli Lilly This is to prevent immune-compromised people infected with Covid from becoming seriously ill, according to the NIH.
As Omicron BA.5 declines, populations with compromised immune systems become increasingly vulnerable, as these new subvariant herds account for about 38% of infections in the United States, according to CDC data. state.
Pfizer’s antiviral drug paxlovid is still effective against the Omicron subspecies, but organ transplant recipients often cannot take the pill because of the way it interacts with the other drugs they need. said Cotton.
“I am concerned that the near future is going to be a difficult time for immunocompromised patients,” said Kotton. “Evusheld’s monoclonal antibody will be less protective, and bebtelovimab will provide ineffective treatment against several emerging variants.”
And there is no assistance at this time. Kotton said he did not recognize monoclonal antibodies ready to replace those that subvariants are scraping off. Jha acknowledged at the White House on Tuesday that as Covid evolves, US treatment and prevention options for people with weaker immune systems are dwindling. accused Congress of failing to provide $22.5 billion in funding to
“As the pandemic progressed and the fight against this virus progressed, we hoped to expand our medicine cabinet,” Jha told reporters. is actually shrinking, putting vulnerable people at risk.”
Finding ways to protect people with compromised immune systems is the most important issue of the current pandemic and needs to be addressed quickly, says Andrew Pekos, a virologist at Johns Hopkins University. said.
“What we really need to work on is getting new antibody therapies out of the lab and into the clinic,” said Pekosz. “In the lab, scientists know what the next generation of monoclonal antibodies will look like.”
Cotton said people with compromised immune systems should get vaccine updates. This means we need to get a new booster that targets the Omicron BA.5. A person who has been kept up to date throughout the pandemic, so far he has had six vaccinations.
According to CDC guidelines, those starting from scratch will receive a three-dose primary series that includes older generation shots from Moderna or Pfizer, as well as a new booster that targets Omicron.
Those with compromised immune systems should continue to be vigilant this winter, Kotton said. But she said the group is more committed than others to wearing masks and practicing mitigation measures to avoid the virus.
The bigger problem is that large portions of the public are on the move and are not taking basic precautions, such as wearing masks, to reduce transmission and protect vulnerable populations, said Cotton. I got
“The more masks we all wear in public, the safer we are and the more likely we are to return to many activities safely,” she said.
Jah told NBC News on Tuesday that Biden’s telling people with weakened immune systems to consult a doctor about precautions shows that the burden of responsibility has shifted to individuals rather than the wider community. I was asked if there was
“As a society, as a compassionate society, we care about all Americans, especially the most vulnerable Americans,” Jah said. “So I think it’s a collective responsibility for all of us to care for our fellow immunocompromised Americans.”
The CDC recommends that people in communities with moderate risk levels for Covid self-test and wear a quality mask before meeting indoors with someone at high risk of getting sick. People exposed to it should wear a quality mask when indoors in public.
With high Covid levels, people generally should consider wearing quality masks and vulnerable people should consider avoiding indoor activities in non-essential public spaces, according to the CDC . You can do it Check your county’s Covid levels on the CDC website.
The mention sources can contact us to remove/changing this article
What Are The Main Benefits Of Comparing Car Insurance Quotes Online
LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos
to request, modification Contact us at Here or [email protected]
- WMU Golf looking for a productive spring
- No. 19 Lions roll past Alabama, 7-0
- Augustana men’s tennis briefs to open season
- See what happens when the wind chill hits -108 degrees on Mount Washington
- Why Microsoft’s $69 billion Activision deal is in London, not Washington
- Doubleheader Dub for Water Polo Featured by Upset Over No. 6Michigan
- Measles warning for NZ flight passengers after case discovery
- Paul Whelan’s brother describes the harsh conditions his brother faces in a Russian prison
- UK family to apologize in Grenada for slave past – BBC News
- World Cancer Day: Closing the Care Gap
- ‘Absurd’: Cupp reacts to GOP criticism of Biden over alleged spy balloons
- Post-Game Notes – Arizona vs. USC