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U.S. prescriptions for hydroxychloroquine surged from February to March, research shows




With the prescription of the antimalarial drug chloroquine Hydroxychloroquine In the US, it soared from February to March. The drug was unproven at that time, but it was being advertised as a remedy for coronaviruses.

Researchers found that the estimated number of hydroxychloroquine prescriptions increased 36.2-fold from February to March, from 367,346 to 683,999, and dispensed chloroquine prescriptions increased by 158.6%, from 2,346 to 6,066. ..

Combination of hydroxychloroquine and antibiotics Azithromycin It was also advertised as a potential treatment for coronavirus infections. According to the analysis, the estimated number of patients receiving the two drugs increased by 1,004% from 8,885 to 101,681 between February and March.

Data published by the journal in a research letter on Monday JAMA Internal Medicine, The prescription ratio of chloroquine and hydroxychloroquine was found to be stable from October 2019 to February 2020. The analysis only looked at the data up to March.

The authors noted that not all prescription increases may apply to Covid-19 because their data do not include the purpose for which the drug was prescribed. Still, they said that with the sudden surge of hydroxychloroquine Chloroquine The prescription may have affected the availability of patients prescribed the drug for use approved by the US Food and Drug Administration, including the treatment of rheumatoid arthritis, lupus and malaria.

The FDA revoked Covid-19’s emergency use permits for hydroxychloroquine and chloroquine on June 15.

Some researchers thought that chloroquine and hydroxychloroquine might be able to fight coronaviruses based on initial laboratory analysis, and President Trump became a cheerleader in therapy, calling it “extreme”. “Encouragement” and “Very powerful” and we called it “Game Changer”.

However, a recent study of Covid-19 patients shows little drug stack-up. A randomized clinical trial-considered the gold standard for determining drug efficacy-was discontinued by the National Institutes of Health after data showed that hydroxychloroquine did not benefit Covid-19 patients. It was.

“No harm, but it’s very unlikely that the study drug would benefit Covid-19 inpatients,” the NIH said in a June 20 news release.

A team at Henry Ford Health Systems in Southeast Michigan announced last week that it found that Covid-19 patients receiving hydroxychloroquine were far less likely to die, but other researchers said. I’m asking about the discovery.

“The whole body of evidence is so much on the side that the drug doesn’t work. Most of the research agrees very closely with that,” said Dr. Neil Schulger. Chairman A member of the School of Medicine at New York Medical College, co-authored an observational study showing that hydroxychloroquine is not associated with intubation or mortality in 1,376 coronavirus patients.

Schulger and other researchers Henry Ford An analysis of teams that may have contributed to the positive findings, such as reduced mortality, may be the result of physicians being proficient in treating Covid-19 patients, regardless of the prescribed treatment.

“Obviously, we all want a cure for this disease,” Schulger said. “But I think we still have to wait.”

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