Connect with us


Does nose picking increase Alzheimer’s risk?

Does nose picking increase Alzheimer’s risk?
Does nose picking increase Alzheimer’s risk?


a new research It was the first to show that it is a bacterium. Chlamydia pneumoniae It can enter the brain via the mouse olfactory nerve. This finding may have implications for neurodegenerative conditions such as Alzheimer’s disease (AD).

Bacteria associated with Alzheimer’s disease

and number of studiesrespiratory tract pathogens Chlamydia pneumoniae It has been identified in postmortem brain samples from AD patients. In the brain, bacterial antigens are localized to amyloid-beta (Aβ) deposits, a classic ‘marking’ symptom of AD.

What is Chlamydia pneumoniae?

respiratory tract pathogens, pneumococcus It can cause infections such as pneumonia. Growing research shows that bacteria are present in diseases other than the respiratory tract. arthritis, multiple sclerosis When late-onset dementia.

somehow pneumococcus Although it is not yet clear that is a ‘contributory factor’ for neurodegeneration, its association with chronic CNS pathology warrants further investigation.A new study by researchers at Griffith University seeks to understand how respiratory pathogens enter the brain. scientific report.

C. pneumonia Infects the olfactory and trigeminal nerves

guided by Dr. Jenny Ekberga researcher who is an associate professor of neurophysiology and a member of the Griffith Institute for Drug Discovery, isolated female mice injected with phosphate-buffered saline or saline. C. pneumonia By intranasal administration.

immunohistochemistry Analysis of the mouse model revealed that C. pneumonia Within approximately 72 hours after injection, both the olfactory and trigeminal nerves can be infected, as well as the olfactory bulb and brain. This bacterium was found to cause deregulation of key pathways known to be involved in AD pathogenesis, both at 7 and 28 days after inoculation.In the olfactory system, Aβ deposition is C. pneumonia.

What are the olfactory and trigeminal nerves?

  • of olfactory nerve Responsible for smell. Its receptors are found in the mucosa under the roof of the nasal cavity.
  • of trigeminal nerve is the largest cranial nerve, transmitting sensory input from the facial region and involved in motor movements such as biting and biting.

“We showed it first pneumococcus It enters the brain directly through the nose and causes conditions like Alzheimer’s disease. ” Said Professor James St. John, director of the Clem Jones Center for Neurobiology and Stem Cell Research at Griffiths and co-author of the study. “We’ve seen this happen in a mouse model, but the evidence is also potentially frightening for humans.”

The team also used a “nasal epithelial injury model” as part of the study. C. pneumonia inoculation. The logic behind this protocol was to investigate whether damage to the epithelium affects risk. C. pneumonia Infection of the central nervous system. “Injury to the nasal epithelium increased peripheral nerve and olfactory bulb infections, but did not alter general CNS infections,” the authors wrote in a publication.

Nose picking is not recommended

Ekberg and colleagues acknowledge that this study needs to be conducted in humans to understand how translatable data lies on the pathway of infection. Based on results from animal studies, St. John suggests several ways to protect the lining of the nose. “We don’t want to hurt the inside of our nose, so we can do that with picking or plucking,” says St. John. Said“Damage to the nasal mucosa can increase the number of bacteria entering the brain.”

As a next step, the researchers plan to extend their research to humans. We are also interested in the impact of their data on her AD diagnosis. Loss of smell is currently classified as an early diagnostic marker for this disease. St. John proposes the introduction of olfactory tests for certain age groups and above so that diseases can be detected as early as possible. Because it’s not just age, it’s also environmental exposure. And I think bacteria and viruses are important,” he concluded.

reference: Chacko A, Delbaz A, Walkden H et al. Chlamydia pneumoniae infects the central nervous system via the olfactory and trigeminal nerves and contributes to the risk of Alzheimer’s disease. science officer2022;12(1):2759. Doi: 10.1038/s41598-022-06749-9.

This article press release Published by Griffith University. The length and content of the material have been redacted.




The mention sources can contact us to remove/changing this article

What Are The Main Benefits Of Comparing Car Insurance Quotes Online

LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos


to request, modification Contact us at Here or [email protected]