Woman survived cancer 12 times, her genes stunned experts

The woman was first diagnosed with cancer when she was 2 years old. (image)

A woman who had 12 types of tumors surprised scientists, according to a Spanish newspaper. CountryA 36-year-old woman whose identity was not disclosed was first treated for cancer at age 2 and was diagnosed with cervical cancer at age 15, according to a case study published in Science Advances. When she turned 20, she had a salivary gland tumor surgically removed. A year later she underwent further surgery to remove a low-grade sarcoma.

By the time she was in her 30s, at least 12 tumors had been detected, 5 of which were malignant. Case Study said further.

Her life has taken medical experts by surprise, and a global team led by the Spanish National Cancer Research Center took her blood samples and began analyzing the reasons behind her condition.

Using single-cell DNA sequencing to help identify mutations in the gene, a team of doctors discovered something strange – women are king of the weird mutations in both copies of the MAD1L1 gene. had a

So far, scientists have discovered that no mouse-like animal with the mutation has ever been born and survived. It was very difficult to understand why. There must have been something else that helped her. spanish press.

The MAD1L1 gene has the machinery that aligns the chromosomes before the baby is born. However, the researchers observed that the female’s double-mutated gene derailed cell growth, says El Pais’ report.

But her susceptibility to cancer, driven by genetic instability, appears to be the answer to her survival. A stimulated immune system favored better identification and destruction of tumor cells.

According to biochemist Carolina Villaroya, “Her genetic defect ultimately protected her. After surgery and treatment, she healed very well from all malignancies. Partly because of her immunity.” Thanks to the system.”

The woman has been tumor-free since 2014. She lives alone, has a job and lives a normal life.

But researchers say her enhanced immune response could help improve cancer diagnosis and develop new treatments.

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