Health
Taking probiotics along with prescribed antibiotics can reduce damage to the gut microbiota
Probiotics mitigate antibiotic-induced changes to the human gut microbiota. Credit: Fernández-Alonso et al., Journal of Medical Microbiology 2022
Millions of antibiotics are prescribed each year. Antibiotics are very effective in treating infections, but usually antibiotics don’t just target the bacteria that are causing the infection. There is evidence that this disruption to gut microbiota composition can persist for up to two years after antibiotic treatment. Gastrointestinal symptoms such as diarrhea and bloating are also common side effects of antibiotic use.
Dr. Elisa Marroquin, assistant professor at Texas Christian University and co-author of the paper, explains: The same thing happens with bacteria. We need many different gut bacteria that know how to do different things.
“Although no single definition of a healthy gut microbiome has yet been found, one thing we see all the time in healthy people is high levels and diversity of bacteria in the gut. ”
In previous studies, probiotics Although it can reduce the gastrointestinal side effects of antibiotics, there has been some debate as to whether taking probiotics along with antibiotics can maintain the diversity and composition of the gut microbiota. mosquito healthcare professional We are reluctant to recommend probiotics alongside antibiotics for fear of further altering the delicate microbial balance in the patient’s gut.
New paper published in Journal of Medical Microbiology We reveal the first systematic review to assess the effects of taking probiotics along with antibiotics on the diversity and composition of the human gut microbiota. Authored by researchers from the Technologico de Monterrey, University of Texas, and Texas Christian University School of Medicine and Health Sciences, the review assesses trends in 29 studies published over the past seven years.
The authors found that taking probiotics along with antibiotics could prevent or attenuate changes in gut microbiota composition caused by antibiotics.Probiotics can also help protect species diversity Additionally, it reduces inflammation and restores numbers of friendly bacteria such as Faecalibacterium prausnitzii, which promotes a healthy intestinal barrier.
“We see consistent changes in some bacterial species when participants take antibiotics,” Marroquin said. , some changes were completely prevented.
“Considering the human data available to date, there does not appear to be any reason to withhold probiotic prescriptions. Antibiotics Prescribed. ”
Additional impact of probiotics to antibiotic interventions on human gut microbial diversity and composition: a systematic review. Journal of Medical Microbiology (2022). DOI: 10.1099/jmm.0.001625
Provided by the Society of Microbiology
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