Health
A single vaccine for the COVID-19 study may be difficult to achieve, according to a U of M study
According to a study from the University of Manitoba, a single vaccine for COVID-19 can be difficult to achieve due to the presence of more than 140 viral variants.
Dr Carlos Falcus, a postdoctoral researcher in pharmacology and therapeutics at Max Lady Medical College and the Institute of Oncology and Hematology, said this too could lead to an increase in false-negative tests due to gene sequence changes. ..
This study is the first to combine genomic sequence data from two global sources to detect regional variants. PeerJ — Journal of Life and Environmental Sciences Released by college on Tuesday in May.
“Viruses evolve differently in different regions,” Farkas said. “It causes problems with trying to develop a single cure or a single vaccine. I think a single vaccine is not possible… I know over time, but it becomes difficult I suppose.”
The test used to detect COVID-19 uses a small piece of DNA called a primer. It binds to the viral sequence and amplifies the viral DNA present in the sample.
Health officials have repeatedly said that the virus does not go away quickly, so it is necessary to learn to live with it.
The SARS-CoV-2 virus is constantly evolving, mutating, and varies by region. This study specifically compared the datasets in Washington, China where it occurred and Victoria, Australia.
Over time, the virus continues to mutate.
What this means is that annual boosters such as influenza vaccination may be the most effective method of vaccination.
“Perhaps in the second wave, the virus mutates so much that it actually becomes a different virus, so the vaccine does not work as efficiently as the first wave,” Farkas said.
Different variants mean that different variants have different effects on the population. This is why COVID-19 has been shown to be transferable to asymptomatic people in some jurisdictions and not transferable elsewhere, or why it attacks certain demographics more than others. is.
“People harbor different strength viruses, which will behave differently within the population,” Falcus said.
Human genetics also influences this, but it was not part of the study.
Farkas and his team are currently following all sequences around the world and expect to publish a new report in the next two months.
He added that people do not have to panic, but they should be educated about the situation.
Twitter: @ JoshAldrich03
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