Health
Here’s how to protect your child’s lungs and immune system from severe Covid-19-Health
Differences in lung physiology and immune function in children may explain why they more often escape from the severe illnesses associated with them. COVID-19 (new coronavirus infectious disease) (# If there is no character limit, add parentheses when first appearing More than adults, according to research, shedding more light on the biological processes behind deadly infections. Scientists, including scientists at the University of Texas health The Science Center in Houston, USA (UTHealth) said that children under 18 make up 22% of the U.S. population, but only about 1.7% of the country’s first 1,49,082 COVID-19 cases belonged. To this age group that I added.
“These significant reductions in symptomatic infections, hospitalization, and mortality far exceed statistical significance, require further testing, and may hold the key to identifying therapeutic agents.” Researcher in the American Journal of Physiology-Lung Cellular and Molecular Physiology.
They said a human molecule called angiotensin-converting enzyme 2, or ACE2, acts as a door for cells to enter the new coronavirus, SARS-CoV-2, and has fewer lungs in children than in adults.
“ACE2 is important in viral entry and increases with age, so it seems less common in children,” says Matthew Harting, co-author of UT Health’s study. Scientists say that, in addition to low ACE2 receptors, children’s immune system responds differently to the adult virus, and pediatric patients have less chance of severe disease. By way of example, they said that there is retention of T cells in the child’s immune system. And it can repel or limit inflammation.
“T cells also have viral and immunomodulatory responses. In severe cases of adult COVID-19 patients, these T cells are depleted, which reduces their ability to fight the virus,” says UT Health. Harry Karmouty-Quintana, another co-author of the study, said. “In children, those T cells seem to be maintained and can prevent the virus,” said Karmouty-Quintana.
According to the researchers, the lung tissue of children is naturally high in regulator T cells. They said that patients with higher levels of T cells also have higher levels of intercellular signaling molecules called interleukin 10 (IL-10), also known as a human cytokine synthesis inhibitor.
“IL-10 suppresses the inflammation of other harmful components such as IL-6. Adults are more likely to experience hyperinflammatory conditions when their children are not.” Studies have also shown that IL-10 decreases with age,” he added. Scientists believe that cooperation between adult and pediatric donors is really important for comparing the behavior of the virus in younger children to the observations made in the elderly.
(This article has been published from the telegraph agency feed with no changes to the text. Only the headings have changed.)
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