Health
Proper hydration may extend life: study
Using health data collected from 11,255 adults over a 30-year period, researchers analyzed the relationship between serum sodium levels (which rise as water intake decreases) and various indicators of health.
Researchers found that adults with serum sodium levels at the high end of the normal range were more likely to develop chronic disease and show signs of biological aging than those with moderate serum sodium levels. Adults with higher levels were also more likely to die at a younger age.
The findings are published in the journal eBioMedicine.
“Results suggest that proper hydration may slow aging and prolong disease-free living. Natalia Dmitrievastudy authors and researchers Cardiovascular Regenerative Medicine Laboratory National Heart, Lung, and blood laboratory (NHLBI), part of the NIH.
For the analysis, researchers assessed information shared by study participants during five medical visits, the first two in their 50s and the last two in those aged 70-90.
To allow a fair comparison of how hydration correlates with health outcomes, the researchers investigated whether adults who had high levels of serum sodium at baseline check-in, or who had no effect on serum sodium levels. They excluded adults with underlying medical conditions, such as obesity, which could give rise.The scientists then evaluated how serum sodium levels correlated with biological aging. This was assessed by 15 health markers. This includes factors such as systolic blood pressure, cholesterol and blood sugar, providing insight into how well each person’s cardiovascular, respiratory, metabolic, renal and immune systems are functioning. The study also adjusted for factors such as age, race, biological sex, smoking status, and hypertension, the study said.
They found that adults with higher levels of normal serum sodium (with normal ranges ranging from 135 to 146 milliequivalents per liter (mEq/L)) were more likely to show signs of faster biological aging. It was based on metrics such as metabolic and cardiovascular health, lung function, and inflammation.
For example, adults with serum sodium levels above 142 mEq/L are 10–15% more likely to be biologically older than chronological age compared to those in the range of 137–142 mEq/L,144 Levels above mEq/L were correlated. with an increase of 50 percent. Similarly, levels of 144.5 to 146 mEq/L were associated with a 21% increased risk of premature death compared to the range of 137 to 142 mEq/L, the study said.
Similarly, adults with serum sodium levels greater than 142 mEq/L have up to a 64% increased associated risk of developing chronic diseases such as heart failure, stroke, atrial fibrillation, peripheral artery disease, chronic lung disease, diabetes and dementia. Did. Conversely, adults with serum sodium levels between 138 and 140 mEq/L had the lowest risk of developing chronic disease, the study said.
The findings do not prove causality, the researchers noted. Randomized controlled trials are needed to determine whether optimal hydration can promote healthy aging, prevent disease, and extend lifespan. can provide and guide individual health behaviors.
“The purpose of providing medical guidance is to ensure that patients are getting enough fluids and to assess factors that may lead to fluid loss, such as medications,” he said. manfred boehmstudy author and director of the Institute of Cardiovascular Regenerative Medicine.
“Physicians may also need to follow the patient’s current treatment regimen, including limiting fluid intake for heart failure,” Boehm said.
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