Coronavirus autopsy: Small blood clots found in a patient, says a pathologist

Dr. Amy Rapkiewicz, Dean of Pathology at NYU Langone Medical Center, spoke to Erin Burnett at OutFront Thursday night.

Although some Covid-19 patients have been found to develop a blood clotting dilemma, the extent and extent of occurrence is referred to by Rapkiewicz as “dramatic.”

During the early stages of the pandemic, bedside clinicians found that there were many blood clots in “a variety of large blood vessels in a row.”

“What we saw at autopsy was like an extension of that,” she said. “Coagulation has occurred not only in large blood vessels, but also in small blood vessels.

“And this was dramatic, because we might have expected it in the lungs, but we found it in almost every organ we examined in our autopsy study,” she said. Said. A study by Lapkievich outlining her findings was published by the end of June in the lancet journal E Clinical Medical.

Necropsy also showed abnormalities with megakaryocytes, or large bone marrow cells. They usually don’t circulate away from the bones and lungs, Lapkiewicz said.

“I found them in the heart and kidneys, liver and other organs,” she said. “Especially in the heart, megakaryocytes produce what are called platelets, which are closely involved in blood coagulation.”
The researchers hope to understand how these cells affect the coagulation of Covid-19’s small blood vessels, she said.

Pathologists are amazed at what they missed.

In the early stages of the pandemic, doctors thought the virus would cause inflammation in the heart with myocarditis, she said.

However, the autopsy revealed very few incidents of myocarditis, Lapkiewicz said.

One of the “opportunities-when the virus has the opportunity to count” was that the pathologist had the opportunity to examine the organs of several Covid-19 victims and investigate the disease processes that occur. she said. She said that the H1N1 and the original outbreak of SARS did not really offer the opportunity.

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