Updated booster cuts risk of XBB variant infection by almost half

In a finding that suggests it’s worth getting an updated bivalent COVID booster shot, new government data shows that the new XBB variant cut the likelihood of infection by almost half.

There was a 48% reduction in risk for those under 49 years of age, but there was a slight decline in vaccination effectiveness among older people, with approximately 40% reduction in adults between the ages of 50 and 64 years and 43% among those aged 65 years and over. A study by the U.S. Centers for Disease Control and Prevention found benefits with both Pfizer and Moderna boosters.

The booster was modified last summer to target Omicron variants BA.4 and BA.5, but the latest research reveals it works against XBB as well. . person in charge About half of new cases in the US.

This is “pretty safe”. Dr. Brendan Jacksonthe CDC’s head of COVID response said at a media briefing on Wednesday. NBC News report. “These latest vaccines are protecting people from the latest of his COVID-19 variants.”

To determine the effectiveness of the latest booster, CDC researchers examined the test results of more than 29,000 adults who tested for COVID symptoms at pharmacies between Dec. 1 and Jan. 13. , compared with boosters and without additional injections.

Many Americans do not take advantage of this special protection: CDC report Only 15% of Americans received updated boosters.

“This data shows that there are advantages that may persuade some people to sign up and get bivalent boosters.” Dr. Peter Hotesco-director of the Vaccine Development Center at Texas Children’s Hospital, said: NBC News.

According to the CDC, the success of these boosters in protecting people is similar to the success of annual flu shots, which typically reduce risks by 40% to 60%.

nevertheless, government data You may not be able to paint the full picture. Neither asymptomatic nor those who may have been hospitalized without being tested at a pharmacy were included. NBC News report.

Those who get boosters may also be protecting themselves in other ways, such as wearing masks indoors or restricting movement. Dr. Greg Polanddirector of the Mayo Clinic Vaccine Research Group, said: NBC News.

Hotez said he would like to see data on amplifier Information on efficacy for performance and hospitalization after 5 and 6 months.

But soon-to-be-released CDC data show that the latest booster reduced the risk of dying from COVID by nearly 13 times compared to those who weren’t vaccinated, Jackson said Wednesday. mortality Those who were boosted were twice as likely to die of COVID after being vaccinated but not boosted.

On Thursday, the U.S. Food and Drug Administration’s vaccination Advisory Board meet Consider agency proposals to turn bivalent COVID boosters into annual shots, much as is done with flu vaccines.

For more information:
Vaccines.gov has more information on identifying COVID-19 vaccination.

Ruth Link-Gelles et al., Efficacy of a bivalent mRNA booster dose vaccine in preventing symptomatic SARS-CoV-2 infection caused by Omicron BA.5– and XBB/XBB.1.5– associated sublineages in immunocompetent adults. Early Estimation—Program to Increase Community Access to Testing, United States, December 2022-January 2023, MMWR.Weekly reports of morbidity and mortality (2023). DOI: 10.15585/mmwr.mm7205e1

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