Food and Drug Administration Advisor on Thursday Unanimously in favor of deprecating the original coronavirus Shot in favor of one that targets both the original strain of coronavirus and the Omicron variant.
Health
FDA advisors favor scrapping original covid shots and using newer versions
“Talking to colleagues, friends, family, and answering questions from the community, we see a great deal of confusion about these different formulations … what we can do to alleviate that confusion and simplify Anything is good,” said Archana Chatterjee, dean of the Medical College of Chicago and a member of the FDA Advisory Board.
The FDA also sought input from advisors on several complex topics, such as whether it should switch to an agency. Annual vaccine schedule This is similar to the annual flu vaccine. Many committee members supported simplification of immunization, but questioned whether boosters should be given to young unvaccinated children and to the elderly and immunocompromised. I asked for more data to understand.
Representatives of three vaccine companies, Moderna, Novavax and Pfizer, said 100 days to six months’ notice is required before a vaccine based on the new variant can be launched. Messenger RNA shots made by Moderna and Pfizer can be manufactured quickly, but several panel members argued that little attention was paid to the potential role of protein-based shots like the one made by Novavax. Did. protection.
Many experts warn that following the flu vaccine model may be a viable option, but the coronavirus has yet to settle into a credible seasonal pattern.
“We have to keep reminding ourselves that this is not the flu. ” said Bruce Guerin, head of global public health strategy at the Rockefeller Foundation.
Many scientists are unhappy with vaccine policies that are always two steps behind the virus and hope there will be better options in the future.
John Beigel, deputy director for clinical research in the Division of Microbiology and Infectious Diseases at the National Institutes of Health, said public health support for a next-generation, variant-proof vaccine that would limit the spread of coronavirus and provide durable protection. I have outlined the need.
But Baigel said identifying promising vaccine candidates will require more scientific work than in the early days of the pandemic.
“For Operation Warpspeed, we had good data to back up which vaccines to go ahead with,” Beigel said, referring to government campaigns to develop vaccines and treatments early in the pandemic. For next-generation vaccines, it’s less clear which vaccine candidates are most likely to succeed, or even how to measure whether they’re working.
“It’s not clear which vaccines are more likely to provide broader protection and greater durability,” Beigel said. Would you like to choose?”
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