Health
Living with the ever-changing SARS-CoV-2
As the new year begins, attention is once again focused on new variants of SARS-CoV-2. The media has repeatedly dealt with so many other subspecies that have come to the predominance that they have run headlines as “the most immune evasive subspecies ever.” As a clinician, I have been inspired to re-examine the availability of treatments and ensure that the treatment of COVID-19 has not changed significantly. But as a citizen, I must admit . Change channels, close news sites, turn pages.
Viruses change. Our immune system adapts to fight them. Then they change again and our immune system adapts again. The main hosts of most viruses are bacteria, not humans. As non-cellular particles that depend on host cells for replication, viruses must change in order to continue to exist. And in what direction will they change? They change towards variants that circumvent current immunity. According to the Centers for Disease Control and Prevention, the US variant since October 2022 has shown this dramatically, with BA.5 he dominated in October, but BQ.1.1/BQ.1 , and by early 2023 he had the upper hand on XBB.1.5. .
This situation has not been monitored as closely as SARS-CoV-2. The pathogen’s history has been unfolding in real-time over the past three years, with more information about the virus and her COVID-19 illness pouring into the public, scientists, and clinicians every day. In the beginning, the need for practical information was so great that treatment ideas continued to emerge without sufficient supporting information. It also led to hot takes by new personalities who rose to fill the data void with declarations of knowledge that didn’t exist. people, those who proclaimed the end of the pandemic during the wave, or those who mocked those who were doing their best to keep their cool while navigating a chaotic world.
This makes for a difficult image to process intelligently. My attempts to do so boil down to acceptance. SARS-CoV-2 is an established virus. The disease, her COVID-19, will not impact society as it has before, but will enter medical textbooks as a respiratory virus that causes serious illness in some people. Modern vaccination efforts remain critical, and COVID-19 vaccines will continue to be developed and modified on an as-yet-unknown schedule. Hopefully, one will be developed soon that provides broad mucosal immunity.
Viruses change and adapt. we have to live with each other.
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