Health
Report: Coronavirus affects not only lung but whole body
Much of the virus damage is due to an affinity for a receptor called ACE2, the report says.
In addition to lung damage, coronavirus also affects the kidneys, liver, heart, brain, nervous system, skin, and digestive tract, a medical team at Columbia University Irving Medical Center in New York City said in a new report. I am.
The medical team at the Center in New York came up with the information in a review report published in the Nature Medicine journal.
The University of Columbia Irving Medical Center was flooded with patients who provided the medical team with real experience. However, they said they had gathered reports from other medical teams around the world on this point.
A review by doctors shows that the coronavirus attacks almost every major system in the human body, directly damaging organs, causing blood to clot, the heart losing a healthy rhythm, the kidneys draining blood and proteins, the skin Shows that a rash erupts.
It also causes typical respiratory symptoms such as coughing and fever such as headaches, dizziness, muscle aches and stomach ache.
Colombian cardiologist Dr Aakriti Gupta said in a statement that he worked on this review. “Doctors should think of Covid-19 as a multisystem disorder.”
“There’s a lot of news about coagulation, but we understand that a significant proportion of these patients have kidney, heart, and brain damage, and doctors need to treat these conditions along with respiratory diseases. That’s also important,” she added.
According to this report, much of the damage done by the virus seems to be due to its affinity for a receptor called ACE2, a gateway for a type of molecule to the cell.
The cells that line blood vessels, kidneys, liver ducts, pancreas, intestines, and respiratory tracts are all covered by the ACE2 receptor, which the virus can use to infect cells, according to medical teams.
The medical team also wrote: “These findings suggest that multiple organ damage may occur, at least in part, due to direct viral tissue damage.”
Coronavirus infection also activates the immune system, the report said. Part of that response involves the production of inflammatory proteins called cytokines.
This inflammation can damage cells and organs, and says the so-called cytokine storm is one of the causes of serious symptoms.
“This virus is abnormal and it’s hard to step back and be impressed by the number of symptoms that appear in the human body,” said Mahesh Madavant, another fellow of heart disease.
The researchers said that the blood coagulation effect appears to be triggered by several different mechanisms: direct damage to the cells lining the blood vessels and interference with various coagulation mechanisms of the blood itself.
Low blood oxygen levels caused by pneumonia can cause blood to clot more easily, and these clots can cause strokes and heart attacks, or stay in the lungs and legs, he added.
The researchers write that the virus affects the immune system and depletes the T cells that the body normally develops to fight off viral infections. “Lymphopenia is a marker of cell-mediated immune disorders and is the primary test result reported in 67-90% of Covid-19 patients.”
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