Cardiovascular disease and death more likely in COVID-19 survivors

New research clearly linked COVID-19 infection It increases the risk of cardiovascular disease and death, both in the short and long term.

of studywas published in cardiovascular researchassessed the association between COVID-19 and cardiovascular disease incidence and mortality.

“Patients with COVID-19 are more likely to develop more cardiovascular disease than uninfected participants, which may contribute to their higher risk of death.” said Ian CK Wong, BSc (Hons) Pharmacy, MSc, PhD, a professor at the university and a Hong Kong researcher and author of the study.

The prospective cohort study consisted of the general population of 7584 COVID-19 patients recruited between 16 March and 30 November 2020. Participants were recruited from the UK Biobank and followed up to 31 August 2021 (up to 18 months).

COVID-19 patients were randomly matched with up to 10 COVID-19-free participants from two cohorts. A contemporary cohort from March 16, 2020 to November 30, 2020, he has not had COVID-19 during this period. There was also a historical cohort from March 16, 2018 to March 30, 2018 to ensure adequate management.

“Historical control cohorts were included to rule out the effects of routine health care services being curtailed or canceled during the pandemic, which led to poor health and mortality even in uninfected individuals. increased,” Wong explained.

COVID-19 patients were matched to two control groups by age and sex within 5 years. Additionally, her 70,000+ non-COVID-19 participants were similar to COVID-19 patients for smoking, diabetes, ethnicity, hypertension, body mass index, deprivation, cardiovascular and other health conditions. The mean age of all study patients was 66 years, and there were approximately equal numbers of men and women.

Researchers used Cox regression to determine the association between COVID-19 and cardiovascular disease and mortality within 21 days of diagnosis (acute phase) and beyond (acute phase).

In the short-term acute phase, the risk of cardiovascular disease was 4.3 times higher in the COVID-19 cohort than in controls. Strikingly, COVID-19 patients were 81.1 times more likely to die in the acute phase than modern and historical cohorts.

In the post-acute phase, COVID-19 patients had a 1.4-fold higher risk of cardiovascular disease and a 5.0-fold higher risk of death than both controls.

Disease severity was also an important indicator of heart disease and mortality in COVID-19 patients. Participants with severe her COVID-19 were more likely to develop major cardiovascular disease or die than those with less severe disease.

The fact that the risk of death in COVID-19 patients remained 5-fold higher 18 months after acute infection deserves close monitoring and further study.

“Our findings suggest that patients with COVID-19 should be monitored for at least one year after recovery from acute illness to diagnose cardiovascular complications of the infections that form part of long-term COVID. It shows that there is,” said Wong.

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