Health
March: Memory Failure | News and Features
Learning, memory, and memory retrieval are supported by multiple distinct neuronal groups connected within and across key regions of the brain. A new study led by the Universities of Bristol and Heidelberg found that memory is lost when these neural assemblies fail to synchronize at the right time.
How do you keep track of what to do next? What happens in your brain when you go blank?Short-term memory relies on two key brain regions in her: the hippocampus and the prefrontal cortex. Researchers set out to establish how these brain regions interact with each other when memories are formed, maintained, and recalled at the level of specific groups of neurons.Research published in current biologyalso wanted to understand why memory sometimes fails.
“Neural assemblies,” groups of neurons working together to process information, were first proposed over 70 years ago, but have proven difficult to identify.
Using rat brain recordings, the research team found that memory encoding, storage, and retrieval are supported by dynamic interactions that incorporate multiple neural assemblies formed within and between the hippocampus and prefrontal cortex. indicated that Animals make mistakes when these assemblies fail to coordinate.
Dr. Michal KucewiczAssistant Professor of Neurology at the Technical University of Gdansk and former PhD student at the University of Bristol and first author, Dr. , our findings identified key processes that determine memory success or failure. These represent viable targets for therapeutic intervention at the level of neural assembly interactions.
Matt JonesProfessor of Neuroscience School of Physiology, Pharmacology and Neuroscience and Bristol Neuroscience “Our findings add evidence that the neural underpinnings of memory are more distributed in anatomical space and dynamic over time than previously thought based on neuropsychological models. To do.”
The next step in research is to use drugs or modulate neural assembly interactions via brain stimulation, which Dr. Kucewicz is currently doing in human patients. We speculate that the same mechanism operates in human patients to restore impaired memory function.
This research MRC, welcomeand Bristol Neuroscience.
paper
‘Distinct hippocampal prefrontal neuronal assemblies coordinate memory encoding, maintenance, and retrievalAleks Domanski, Michal T. Kucewicz, Emma SJ Robinson, Matt W. Jones et al.of biology today
Further information
Dr. Michal Kucewicz led all experiments while completing his PhD at the University of Bristol. Michal is currently Brain and Mind Electrophysiology Laboratory at Gdansk Technical University.
Michal’s research is developing electrical brain stimulation techniques to improve memory in patients suffering from epilepsy, Parkinson’s disease and other neurodegenerative diseases. His research goal is to discover the mechanisms of human memory and mind.
About Bristol Neuroscience
Bristol Neuroscience (BN) is a research network supported by. Elizabeth Blackwell Institute for Healthone of the five colleges of the University of Bristol University research institute.
BN was established by the University of Bristol in 2003 to enable all Bristol neuroscientists to benefit from the extensive multidisciplinary expertise and facilities of the University and its affiliated hospitals. It has since become a model for other cities across the UK.
BN’s expertise spans from molecular and cellular neuroscience to patient-based clinical research, including areas of interest such as human cognition, synaptic plasticity, stress and dementia.
follow @BristolNeurosci on Twitter
Sources 2/ http://bristol.ac.uk/news/2023/march/memory-failure.html The mention sources can contact us to remove/changing this article |
What Are The Main Benefits Of Comparing Car Insurance Quotes Online
LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos
to request, modification Contact us at Here or [email protected]