Stroke Health News Related to Delirium, Rare Brain Inflammation, and Coronavirus COVID-19

London: According to recent studies, neurological complications of COVID-19 include delirium (abrupt changes in the brain that cause confusion and emotional confusion), brain inflammation, stroke, and nerve damage.

A study led by a research team at University College London (UCL) and University College London Hospital (UCLH) was published in Brain. It has identified one rare, sometimes fatal, inflammatory condition known as ADEM that appears to have an increased prevalence due to pandemics.

Some patients in this study did not experience severe respiratory symptoms, and neuropathy was the first major symptom of COVID-19.

Co-lead author Dr. Dr. Michael Zandy, UCL Queen Square Institute of Neurology and University College London Hospital NHS Foundation Trust, said, “There are neurological conditions such as brain inflammation that have not always correlated with severity. People have identified more than expected of respiratory symptoms.”

“We need to be vigilant and watch out for these complications in people infected with COVID-19. Whether an epidemic is seen in massive brain damage associated with pandemics-probably in the 1920s and 1930s. It’s similar to the development of lethargic encephalitis. After the influenza pandemic of 1918-not yet seen,” Zandy added.

This study provides a detailed description of neurological symptoms in 43 (16-85 years) treated at UCLH National Neurosurgery Hospital with confirmed or suspected COVID-19.

The researchers identified 10 cases of transient encephalopathy with delirium (temporary brain dysfunction). This is consistent with other studies that find evidence of agitated delirium. There were 12 cerebral inflammations, 8 strokes, and 8 with neuropathy, mainly Guillain-Barre syndrome (usually after respiratory or digestive infections).

Most people with inflammatory brain conditions (9 of 12) were diagnosed with acute disseminated encephalomyelitis (ADEM).

ADEM is rare and is usually found in children and can be caused by a viral infection. The London team usually sees about one adult patient with ADEM per month, but increased to at least one weekly for the duration of the study. Increased concern.

The viruses that cause COVID-19 and SARS-CoV-2 were not detected in the cerebrospinal fluid of any of the patients tested, suggesting that they did not directly attack the brain to cause neurological disease it was done.

Further research is needed to determine why patients develop these complications.

In some patients, researchers found evidence that brain inflammation was probably caused by the immune response to the disease, and some neurological complications of COVID-19 were due to the immune response rather than the virus itself. Suggests that you may be doing it.

The findings are clinically explained in another recent study in which Dr. Zandy and co-author Dr. Hadimanji (UCL Queen Square Neurological Institute) identified 153 people with neurological complications from COVID-19. And adding details.

This paper also confirms a higher-than-expected number of previously reported findings in stroke patients due to excessive stickiness of blood in COVID-19 patients.

Co-author Dr. Ross Paterson (UCL Queen Square Neurological Institute) said, “What could COVID-19 bring to us, given that this disease has only been occurring for a few months? You may not know.”

“Physicians need to be aware of possible neurological consequences because early diagnosis can improve patient outcomes. People who recover from the virus are more likely to be concerned about professional health if they experience neurological symptoms.” I need to seek advice.”

“Our research promotes an understanding of the different ways Covid-19 affects the brain.” Co-lead author Dr. Rachel Brown (UCL Queen Square Neurology and UCL Institute for Infections and Immunology) Manage the treatment and recovery of.”

“Our study, for the first time, fused the clinical picture of a patient with Covid-19 neurological disease with laboratory features including MRI and in one case brain biopsy,” co-author Dr. Hadi Manji said.

This currently sets a template for other researchers around the world and facilitates coordinated research to optimize the diagnosis and treatment of these previously difficult complications.

“In addition, patients will require long-term follow-up,” added the senior author.