Health
Immunity may last only a few months after infection, research found
Immunity to coronavirus in people who recover from the infection may last only a few months, two separate studies have suggested.
Scientists at King’s College in London analyzed 90 patients and health workers in the NHS Foundation Trust in Guys and St. Thomas to peak antibody levels in the immune system three weeks after the onset of symptoms. I have found
In the first longitudinal study of its kind, 60% of participants had a “strong” antibody response in the pain of the virus, which dropped to only 17% after 3 months.
Antibody levels that were 23 times more depleted within three months after infection and were undetectable in some participants.
Boris Johnson has previously declared that antibody testing may be a “game changer” in the fight against the virus, and early in the pandemic, the government issues health certificates to those who contract the virus. I considered that.
Kings College research results, which have not yet been peer-reviewed, raise the likelihood that those who have overcome the virus may be re-infected during future outbreaks.
Researchers in Munich also found that those who recovered from the coronavirus could be vulnerable to a second infection after they also revealed that the antibody weakened over time.
A blood test performed on Covid-19 patients collected at the Schwabing Clinic showed that the levels of antibodies produced by the immune system were, in most cases, significantly reduced.
“We found reduced levels of neutralizing antibodies in four out of nine patients,” said chief investigator Clemens Wentner.
The study was conducted on the first confirmed German case of illness in January.
“How much is [our findings] It affects long-term immunity and vaccination strategies are currently speculative, but this needs to be carefully monitored in the future of the project. “
The findings are consistent with a study conducted in China that concluded that the antibody response was not sufficient to generate lasting immunity.
Doctors at Chongqing Medical University found that the presence of IgG, one of the major antibodies elicited by infection, was reduced by an average of 70% over three months.
This result not only weakens the hope of long-term immunity in infected people, but it also influences the development of successful vaccines.
In the US trials by pharmaceutical giant Pfister, it’s expected this month that a vaccine will be in the pipeline to successfully develop antibodies against coronavirus.
Participants in the trial showed higher levels of antibodies than those previously developed by those infected with the disease.
But now many doctors believe that vaccines have to do more than just drive antibody responses.
Doctors at research facilities in Sweden and California highlighted that T cells may play a more important role in fighting the virus in the long run. Antibodies attack the virus before fixing it to cells, while T cells learn to kill the virus and the cells it infects.
A study conducted by the La Jolla Institute in California found T cells in blood samples taken before the corona outbreak responded to the virus.
“I believe that the optimal design of a vaccine is to elicit both antibody and T cell responses,” said Dr. Alessandro Sette of the Research Center to Reuters.
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