Health
Oxford’s malaria vaccine gets approval for use in Ghana
A malaria vaccine called R21/Matrix, developed by scientists at the University of Oxford, has been approved for use in Ghana.
TheCable had report This vaccine was said to be 80% effective in preventing malaria.
Currently, the only World Health Organization (WHO)-approved vaccine against malaria is the RTS,S/AS01 (RTS,S) vaccine, which is 29% effective in preventing severe malaria.
In a statement Thursday, the University of Oxford said it was the first vaccine in the world to receive regulatory approval.
The vaccine has shown high levels of efficacy and safety in a phase II trial, according to the university, which included a booster dose of R21/Matrix-M one year after the first three dosing regimens. including children.
“This vaccine is approved for use in children aged 5 to 36 months, the age group most at risk of dying from malaria. It is hoped that it will be able to help people fight malaria effectively.
“The R21/Matrix-M malaria vaccine is a mass-manufacturable, low-cost, low-dose vaccine that could supply hundreds of millions of doses to African countries suffering from the severe burden of malaria.
“The R21/Matrix-M vaccine was originally designed and developed at the University of Oxford and is undergoing clinical trials in the UK, Thailand and several African countries, including ongoing trials in Burkina Faso, Kenya, Mali and Tanzania. It includes the phase III trials of , which are enrolling 4,800 children.The results of these trials are expected to be reported later this year.”
Adrian Hill, principal investigator of the R21/Matrix-M program, said the approval was the culmination of 30 years of malaria vaccine research at Oxford.
“We congratulate our wonderful clinical trial partners in Africa for producing data sets that support the safety and efficacy of our vaccines in children. Our partnership with the Serum Institute in India, as well as Oxford and AstraZeneca’s COVID-19 vaccines.” has been the key to the success of very large-scale manufacturing and rapid development.”
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