Health
Diabetes drugs for weight loss may have heart benefits – NBC 5 Dallas Fort Worth
While certain classes of drugs have become popular drugs for weight loss, researchers have found that they can also have potential heart benefits.
Known under brand names such as Ozempic and Wegovy, these approved treatments for people with type 2 diabetes have recently been highlighted for their ability to treat obesity and help people with and without diabetes lose weight.
Darren McGuire, Ph.D., professor of internal medicine at UT Southwestern and member of the Department of Cardiology, was part of an ongoing study showing that the drug reduces the risk of cardiovascular death, heart attack, and stroke.
“This is turning the world of type 2 diabetes upside down. ,” said Dr. McGuire.
McGuire said that during clinical trials, the drug reduced the risk of heart attack and stroke in people with type 2 diabetes by an average of 14% by stabilizing plaque in arteries.
A class of drugs called GLP-1 RA contains a key ingredient called semaglutide and is commonly used off-label by non-diabetics trying to lose weight.
McGuire said that while expensive, it should be the first line of defense when it comes to heart health for the right patients.
“Especially when these drugs become generic, there is a real potential for expanding their use to patients who are at high risk of developing both cardiovascular disease and diabetes.
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